The FDA is uncertain whether the reactions are caused by the active ingredient

The fda is uncertain whether the reactions are caused

This preview shows page 6 - 7 out of 10 pages.

The FDA is uncertain whether the reactions are caused by the active ingredient (ie, benzoyl peroxide, salicylic acid), inactive ingredients, or a combination of both. For more information, see Serious Allergic Reactions Possible With Acne Products, FDA Says . Medication Summary The following information primarily pertains to the treatment of Cutibacterium (formerly Propionibacterium ) acne vulgaris. Antibiotics used to treat anaerobic infections usually suffice for other types of Cutibacterium (formerly Propionibacterium ) infections. These include the penicillins, carbapenems, and clindamycin. In addition, vancomycin and teicoplanin (investigational) have been used. Some of these antibiotics are discussed after the treatment of acne vulgaris. Daptomycin has been used for the treatment of Cutibacterium (formerly Propionibacterium ) osteomyelitis. [ 41 ] Acne Products Class Summary Acne products are used for the treatment of mild to moderate acne vulgaris. These agents may have antibacterial and comedolytic properties. In severe cases, the agents may be used as an adjunct in therapeutic regimens. Erythromycin and benzoyl peroxide (Benzamycin) View full drug information This combination agent contains erythromycin, which is a macrolide antibiotic, and benzoyl peroxide. Benzoyl peroxide, in addition to being an antibacterial agent, is a keratolytic and desquamative agent. With benzoyl peroxide, free-radical oxygen is released upon administration, oxidizing bacterial proteins in sebaceous follicles and decreasing the number of anaerobic, bacterial, and irritating free fatty acids. This combination has keratolytic and comedolytic effects. Erythromycin is indicated for infections caused by susceptible strains of microorganisms. The combination drug may be applied topically twice daily. Clindamycin and tretinoin (Ziana, Veltin) View full drug information This combination agent contains the topical antibiotic clindamycin 1.2% and tretinoin 0.025%. Clindamycin reduces Cutibacterium acnes (formerly Propionibacterium acnes ) levels and is anti- inflammatory. Tretinoin normalizes differentiation of keratinocytes and is anti-inflammatory. Apply daily to affected areas. Clindamycin and benzoyl peroxide (Acanya, Duac, BenzaClin) View full drug information This combination agent contains the topical antibiotic clindamycin and benzoyl peroxide. Clindamycin reduces C acnes (formerly P acnes ) levels and is anti-inflammatory. Benzoyl peroxide is an antibacterial, comedolytic, and anti-inflammatory agent. Benzoyl peroxide reduces the risk of development of bacterial resistance to clindamycin. Acanya gel contains 2.5% benzoyl peroxide and Duac CS and BenzaClin contain 5% benzoyl peroxide. Apply Acanya and Duac CS once daily. BenzaClin is applied twice daily. Azelaic acid (Azelex, Finacea) View full drug information Azelaic acid has been shown to help reduce inflammation and may aid in the treatment of postinflammatory hyperpigmentation. Apply azelaic acid twice daily. Improvement may be seen within 4 weeks.
Image of page 6
Image of page 7

You've reached the end of your free preview.

Want to read all 10 pages?

  • Fall '20
  • V,b,n,
  • acne

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern

Stuck? We have tutors online 24/7 who can help you get unstuck.
A+ icon
Ask Expert Tutors You can ask You can ask You can ask (will expire )
Answers in as fast as 15 minutes