3 briefly describe 50 words or less how mauveine was

3. Briefly describe (50 words or less) how mauveine was discovered and by whom.

4. Describe (25 words or less) one contribution for each of the following three
chemists to the field of aromaticity: Friedrich August Kekulé, Erich Hückel,
Franz Sondheimer; and name and draw the molecular structures of three aromatic
compounds.

Chapter 9: Quinine
1. Briefly describe (100 words or less) how malaria and quinine have influenced our
society throughout time.
2. Explain the role of each of the following in the story of malaria and quinine:
a) Plasmodium falciparum
b) The Incas
c) The Chincona tree
d) The Melinda and Bill Gates Foundation

3. Name the contributions of the following chemists to the chemistry of quinine:
a) Joseph Bienaimé Caventou and Pierre Joseph Pelletier
b) Paul Rabe
c) Robert B. Woodward
d) Gilbert Stork

Chapter 10: Morphine
1. Draw clearly, including stereochemistry, the molecular structures of two of the
following molecules: morphine, codeine, heroin, cocaine and caffeine.
2. One of the critical steps in the first total synthesis of ( ± )-morphine involved a
Diels–Alder reaction, whereas a subsequent asymmetric synthesis of (–)-
morphine involved a catalytic asymmetric allylic ether formation. Answer the
following questions about these historical accomplishments.
a) Name the main scientist involved in each of these syntheses.
b) Name and draw the structure of the diene employed in the Diels–Alder
reaction of the first synthesis.
c) Draw and name the catalyst used for the allylic ether formation in the
subsequent asymmetric synthesis.

3. The reaction of para -quinone and cyclopentadiene gives rise to a 1:1 adduct.
Using molecular structures depict this powerful reaction and name its discoverers.
4. Write informative notes on the following people or items (10 words or less).
h) Morpheus
i) Laudanum
j) Kenichi Fukui

Chapter 11: Steroids & the Pill
1. Give the molecular structures, including stereochemistry, of cholesterol and
estrone.
2. Briefly describe the contribution of the following important key players in the
chemistry of steroids (10 words or less):
a) Werner E. Bachmann
b) Robert B. Woodward
c) William S. Johnson
d) K. Peter C. Vollhardt
e) Adolf O. R. Windhaus
f) Carl Djerassi

g) Russell E. Marker
h) Margaret Sanger
i) Gregory Pincus
4. R. B. Woodward, Sir Derek Barton, and George Olah each won a Nobel Prize for
their important discoveries in chemistry. Briefly describe their contributions (50
words or less, for each).

Chapter 12: Strychnine
1. For what is the molecule of strychnine most famous (or infamous)?