L07 - NATS1610-fw1718 - The Cytoskeleton.pdf

Organisms and sperm n cilia can move fluid over a

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organisms and sperm n Cilia can move fluid over a surface n i.e, sweeping mucus along the respiratory surfaces or moving an egg through the fallopian tube 10 Left – Fig. 3.14 B and C, from Starr and McMillan, Human Biology , 10ed, Brooks Cole cilia Right – Fig. 3.15, from Starr and McMillan, Human Biology , 10ed, Brooks Cole Flagella/Cilia - A circle of nine DOUBLE microtubules surrounds a central pair of single microtubules, forming a 9 + 2 complex, surrounded by a cell membrane Basal Body - TRIPLETS of microtubules forming a nucleation site for flagellar/ cilia microtubules
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11 Fig. 3.22a and 3.22b – from Goodenough and McGuire, Biology of Humans , 2ed, Pearson Prentice Hall
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n Microtubules provide tracks along which vesicles move between the cell interior and the plasma membrane n Microtubules move and separate chromosomes during cell division n MOTOR PROTEINS move vesicles and chromosomes along microtubule tracks Left - Fig. 9.5 - from Starr and Taggart, Biology: The Unity and Diversity of Life , 9ed, Brooks/Cole Centrioles Separating chromosomes Lower Right - Fig. 15.13e-1, – from: Brooker et al., Biology, 1ed, McGraw-Hill Upper Right - Fig. 7.21b, from: Campbell and Reece, Biology , 6ed, Pearson publishing as Benjamin Cummings Vesicle 12
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13 The Cytoskeleton and Motor Proteins Inner life of a cell (3.09 min version) https://www.youtube.com/watch? v=wJyUtbn0O5Y Credits Title: Inner Life of the Cell animation conception and scientific content by Alain Viel and Robert A. Lue. Animation by John Liebler/XVIVO.
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MICROFILAMENTS n Microfilaments are the THINNEST class of cytoskeletal fibres n 7 nm diameter n Also called actin filaments n Solid rods composed of globular protein subunits called ACTIN n An ACTIN FILAMENT consists of a twisted double chain of actin subunits ( 2 chains, twisted together) n DYNAMIC structures - Change length by addition and loss of actin subunits 14 Table 4.1-3 – from Brooker et al., Biology , 1/ed, McGraw-Hill
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