A 52-year-old man has weight of 4 kg over the past 6 months, along with bruises on his skin with even minor trauma and back pain. He has smoked 2 packs a cigarettes per day for 35 years. On physical examination he has obesity in a truncal distribution, plethora, and a blood pressure of 160/110 mmHg. A radiograph of the spine reveals a compressed fracture of T11. Which of the following neoplasms is he most likely to have?
Question 30A 41-year-old man has been drinking large quantities of water--up to 20 liters per day--for the past week. On physical examination he has diminished skin turgor and dry mucous membranes. Laboratory studies show sodium 162 mmol/L, potassium 4.1 mmol/L, chloride 121 mmol/L, and bicarbonate 27 mmol/L. His serum glucose is 75 mg/dL and creatinine 1.0 mg/dL. His serum osmolality is 343 mOsm/kg. A deficiency of which of the following hormones ismost likely present in this man?