Fiehn BIS103 lecture 12_fall 2010

5 the volatile compounds are perceived by a given set

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5 The volatile compounds are perceived by a given set of receptors and release of cation signals which are combined as pattern in different parts of the brain -PP i adenylate cyclase +H 2 O phosphodiesterase Taste is a combined pattern of five different flavors umami is a novel flavor Synthetic compounds can activate ‘sweet’ receptors
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6 Vision: a single photon can be perceived by isomerization of the isoprenoid 11-cis-retinal to all-trans-retinal (bound as Schiff base to lysine-residue in Rhodopsin) Vision: Vitamin A1 is the precursor for 11-cis retinal and derived from β -carotene
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7 Vision: 11-cis-retinal is the chromophor in all organisms. 11-cis retinal has an absorption maximum at 380 nm but is largely influenced by different opsin proteins which are different between species. Vitamin D is an isoprenoid derived from cholesterol and formed in several steps in different organs 2 steps (in skin) 1 step (in liver) 1 step (in kidney)
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8 Other important isoprenoids Other vitamins are derived from pyrrols pyrrol
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9 Some hormones are derived from isoprenoids Some hormones are derived from C20-fatty acids
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