Phosphatidylcholine specific phospholipase c from

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Phosphatidylcholine-specific phospholipase C from Listeria monocytogenes is an important virulence factor in murine cerebral listeriosis. Infect. Immun. 66, 5930–5938. Schneider, S., Bosse, F., D’Urso, D., Muller, H., Sereda, M. W., Nave, K., et al. (2001). The AN2 protein is a novel marker for the Schwann cell lineage expressed by immature and nonmyelinating Schwann cells. J. Neurosci. 21, 920–933. Frontiers in Cellular and Infection Microbiology May 2014 | Volume 4 | Article 51 | 20
Wood and Paterson Listeria monocytogenes as a vector for tumor immunotherapy Schnupf, P., Portnoy, D. A., and Decatur, A. L. (2006). Phosphorylation, ubiquitina- tion and degradation of listeriolysin O in mammalian cells: role of the PEST-like sequence. Cell. Microbiol. 8, 353–364. doi: 10.1111/j.1462-5822.2005.00631.x Schnupf, P., Zhou, J., Varshavsky, A., and Portnoy, D. A. (2007). Listeriolysin O secreted by Listeria monocytogenes into the host cell cytosol is degraded by the N-end rule pathway. Infect. Immun. 75, 5135–5147. doi: 10.1128/IAI.00164-07 Schwartz, K. T., Carleton, J. D., Quillin, S. J., Rollins, S. D., Portnoy, D. A., and Leber, J. H. (2012). Hyperinduction of host beta interferon by a Listeria monocytogenes strain naturally overexpressing the multidrug efflux pump MdrT. Infect. Immun. 80, 1537–1545. doi: 10.1128/IAI.06286-11 Seavey, M. M., Maciag, P. C., Al-Rawi, N., Sewell, D., and Paterson, Y. (2009a). An anti-vascular endothelial growth factor receptor 2/fetal liver kinase-1 Listeria monocytogenes anti-angiogenesis cancer vaccine for the treatment of primary and metastatic Her-2/neu + breast tumors in a mouse model. J. Immunol. 182, 5537–5546. doi: 10.4049/jimmunol.0803742 Seavey, M. M., Pan, Z. K., Maciag, P. C., Wallecha, A., Rivera, S., Paterson, Y., et al. (2009b). A novel human Her-2/neu chimeric molecule expressed by Listeria monocytogenes can elicit potent HLA-A2 restricted CD8-positive T cell responses and impact the growth and spread of Her-2/neu-positive breast tumors. Clin. Cancer Res. 15, 924–932. doi: 10.1158/1078-0432.CCR-08-2283 Seavey, M. M., and Paterson, Y. (2009). Anti-Angiogenesis immunotherapy induces epitope spreading to Her-2/neu resulting in breast tumor immunoediting. Breast Cancer (Lond.) 1, 19–30. Sevil Domenech, V. E., Panthel, K., Meinel, K. M., Winter, S. E., and Russmann, H. (2007). Pre-existing anti-Salmonella vector immunity prevents the devel- opment of protective antigen-specific CD8 T-cell frequencies against murine listeriosis. Microbes Infect. 9, 1447–1453. doi: 10.1016/j.micinf.2007.07.010 Sevil Domenech, V. E., Panthel, K., Winter, S. E., and Russmann, H. (2008). Heterologous prime-boost immunizations with different Salmonella serovars for enhanced antigen-specific CD8 T-cell induction. Vaccine 26, 1879–1886. doi: 10.1016/j.vaccine.2008.01.044 Sewell, D. A., Douven, D., Pan, Z. K., Rodriguez, A., and Paterson, Y. (2004a). Regression of HPV-positive tumors treated with a new Listeria mono- cytogenes vaccine. Arch. Otolaryngol. Head Neck Surg. 130, 92–97. doi: 10.1001/archotol.130.1.92 Sewell, D. A., Pan, Z. K., and Paterson, Y. (2008). Listeria-based HPV-16 E7 vaccines limit autochthonous tumor growth in a transgenic mouse model for HPV- 16 transformed tumors. Vaccine 26, 5315–5320. doi: 10.1016/j.vaccine.2008. 07.036 Sewell, D. A., Shahabi, V., Gunn, G. R., 3rd., Pan, Z. K., Dominiecki, M. E., and Paterson, Y. (2004b). Recombinant Listeria vaccines containing PEST sequences are potent immune adjuvants for the tumor-associated antigen human papillomavirus-16 E7. Cancer Res. 64, 8821–8825. doi: 10.1158/0008- 5472.CAN-04-1958 Shahabi, V., Reyes-Reyes, M.,

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