Controls hormones in the gonads ovaries and testes Sex hormones steroids

Controls hormones in the gonads ovaries and testes

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Controls hormones in the gonads (ovaries and testes) Sex hormones (steroids) Thyroid-stimulating hormone Also called thyrotropin Controls hormone synthesis and secretion in the thyroid Thyroid hormones (amines) Adrenocorticotrophic hormone Also called adrenocorticotropin Controls hormone synthesis and secretion in the adrenal cortex cortisol (steroid)
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Feedback Loops Are Different in the Hypothalamic-Pituitary Pathway The hormone, not the response, is the feedback signal Long-loop negative feedback Peripheral endocrine gland produces hormone that suppresses secretion of anterior pituitary and hypothalamic trophic hormones Most dominant feedback mechanism Short-loop negative feedback Pituitary hormone suppresses hypothalamic trophic hormone production Secondary feedback mechanism Ultra-short-loop negative feedback Occurs in hypothalamus and pituitary Autocrine or paracrine signals to regulate secretion
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Figure 7.11 Negative feedback in complex endocrine pathways Hypothalamus (IC 1 ) Trophic hormone (H 1 ) Anterior Pituitary (IC 2 ) Trophic hormone (H 2 ) Endocrine Gland (IC 3 ) Hormone (H 3 ) Target tissue Response Short-loop negative feedback L o n g - l o o p n e g a t i v e f e e d b a c k Stimulus Adrenal cortex CRH ACTH Cortisol Target tissue To target tissue L o n g - l o o p n e g a t i v e f e e d b a c k Response Hypothalamus Anterior pituitary (b) Control Pathway for Cortisol Secretion Cortisol is a steroid hormone secreted by the adrenal cortex. ACTH = corticotropin or adrenocorticotropic hormone; CRH = corticotropin-releasing hormone. (a) In complex endocrine pathways, the hormones of the pathway serve as negative feedback signals. Short- loop negative feedback occurs with prolactin, growth hormone, and ACTH.
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  • Spring '08
  • Staff
  • Thyroid-stimulating hormone, Stores hormones

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