All cause mortality CVD incidence Cancer incidence Overall 05 1 15 2 25 Hazard

All cause mortality cvd incidence cancer incidence

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All cause mortality CVD incidence Cancer incidence Overall 0 0.5 1 1.5 2 2.5 Hazard Ratio *Adjusted for physical activity Biswas et al Ann Intern Med, 2015
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The relationship between body weight, calorie intake, and physical activity. Mayer J. 1956 Am J Clin Nutr Why Do We Need Exercise? Normal activity range Sedentary zone Normal activity range Sedentary zone
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Trends for Job based physical activity, 1960 - 2008 Large decrease in jobs that require physical activity! Increase in sedentary jobs!! Church et al. PLoS One, 2011 Why do we need Exercise?
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Obese women have lower PA and greater sitting time per day compared with lean women. Why do we need PA? Johannsen DL, Obesity , 2008
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Some exercise may promote weight loss….. More exercise may not produce additional weight loss….. Exercise and Weight Loss Church et al. PLoS One, 2009 .
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Exercise and Weight Loss Church et al. PLoS One, 2009 . Individual weight changes in DREW Predicted Wt. Loss Swift et al. Obesity, 2016 . CLW = 5%
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Exercise and Weight Loss Church et al. PLoS One, 2009 . Weight Compensation Predicted – Actual EE
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Exercise and Weight Loss Stewart et al. MSSE, 2011. Chronic inflammation (CRP) is reduced with exercise, but only in those with significant weight loss.
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Exercise and Weight Loss Swift et al. Obesity, 2016 . Effect of weight loss with exercise on markers of insulin sensitivity: HOMA-IR – fasting insulin and glucose values HOMA-2 – calculator Significant reductions in insulin resistance with exercise and weight loss. NOTE: Subanalysis in exercisers only
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Jackson et al. Arch Intern Med, 2009 Non-linear decline in cardiorespiratory fitness in men and women with age. Can exercise: 1. Reduce/reverse the decline in fitness? 2.If so, what is the minimal, required, and optimal dose?
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051015202530WomenMenCVD Mortality Rates by Fitness: Aerobic Center Longitudinal Study (ACLS)Blair SN et al. JAMA1989;262:2395-2401.Deaths per 10,000 person-yearsLowModerateHigh
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  • Fall '09
  • MICHEALWELSCH
  • kinesiology, Diabetes, physical activity, National Diabetes Surveillance

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