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A major change in bone tissue that occurs with aging

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17) A major change in bone tissue that occurs with aging and that leads to increased brittleness is _____. A) demineralization B) decreased protein synthesis 3
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C) increased bone remodeling D) all of the above Answer: B Topic: AGING AND BONE TISSUE 18) In fetal development, mesenchymal (mesodermal) cells develop into: 19) Osteoporosis may weaken bone to the extent that a small stress will result in a fracture. Such fractures are referred to as _____ fractures. 20) Abnormal acceleration of the remodeling process results in a condition termed Paget’s disease in which bone deformity results and the newly formed bone becomes hard and brittle and fractures easily. Normal bone growth and bone replacement depend on the presence of: TRUE/FALSE. Write "T" if the statement is true and "F" if the statement is false. 21) The connective tissue found on the articular surface at the end of a bone is called endosteum. Answer: FALSE Topic: ANATOMY OF A BONE 22) Bone matrix contains crystallized mineral salts called hydroxyapatite. Answer: TRUE Topic: HISTOLOGY OF BONE TISSUE 23) In matrix formation, calcification precedes the secretion of collagen by osteoblasts. Answer: FALSE Topic: HISTOLOGY OF BONE TISSUE 24) Microscopic canals that run longitudinally through bone tissue and that contain blood vessels and nerves are called perforating (Volkmann's) canals. Answer: FALSE Topic: HISTOLOGY OF BONE TISSUE 4
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25) The nutrient artery of a long bone branches into proximal, distal, epiphyseal, and metaphyseal branches, and therefore supplies the entire bone with blood. Answer: FALSE Topic: BLOOD AND NERVE SUPPLY OF BONE 26) The perichondrium of the cartilage model becomes the periosteum of compact bone. Answer: TRUE Topic: BONE FORMATION 27) Primary ossification proceeds from the external surfaces inward; secondary ossification proceeds from the interior outward toward the external surface of a bone. Answer: TRUE Topic: BONE FORMATION 28) Most bones develop in a process whereby hyaline cartilage models are replaced by bone tissue. Answer: TRUE Topic: BONE FORMATION 29) As a long bone grows in length, new cartilage cells are produced on the epiphyseal side of the epiphyseal plate and bone replaces cartilage on the diaphyseal side of the plate. Answer: TRUE Topic: BONE GROWTH 30) Following completion of ossification, bone replacement occurs only if bone tissue is injured.
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