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So the negative feedback works to keep the blood

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sending this message (insulin), the cells in the body stop taking extra glucose out of the blood. So the negative feedback works to keep the blood glucose level normal. If glucose is high, the pancreas makes insulin. The insulin causes the glucose to fall. Then this lower level of glucose tells the pancreas to stop making insulin
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Introduction to Hormones/Pituitary Function/Adrenal Function – Objectives 3. Describe the clinical utility of each of the following hormones: Growth Hormone, Prolactin, Oxytocin, Vasopressin, ACTH, Aldosterone, Cortisol, DHEAS, Testosterone GROWTH HORMONE – Increases in GH indicate acromegaly, pituitary tumors, gigantism, and pregnancy; Decreases in GH indicate pituitary GH deficiency, hypopituitarism (congenital or acquired), GH secretory dysfunction, and dwarfism PROLACTIN – primarily used in diagnosing and managing pituitary adenomas and the differential diagnosis of male and female hypogonadism; Increases indicate hypothalamic or pituitary tumors, stress, antidepressants, and breast feeding; Decreases indicate bromocriptine (dopamine agonist) OXYTOCIN – has a critical role in lactation and plays a major role in inducing labor; Pitocin is a synthetic oxytocin used in obstetrics to induce labor VASOPRESSIN – (ADH) Antidiuretic hormone; has an essential role in water balance since it’s action is to regulate renal free water excretion; as plasma osmolality increases, vasopressin secretion increases – the consequence is a reduction in renal free water clearance, a lowering of plasma osmolality, and a return to homeostasis; vasopressin is releases in response to a fall in blood volume or blood pressure; Diabetes insipidus (DI), characterized by copious production of urine (polyuria) and intense thirst (polydipsia), is a consequence of vasopressin deficiency; diabetes insipidus vasopressin deficiency is characterized by intense thirst, polyuria, glucose negative, and low specific gravity ACTH – Adrenocorticotropin hormone; regulates adrenal steroidogenesis; ACTH acts on the cells of the adrenal cortex, stimulating them to produce glucocorticoids (like cortisol) mineralocorticoids (like aldosterone) and androgens (male sex hormones, like testosterone) Production of ACTH depends on the intermittent arrival of corticotropin- releasing hormone (CRH) from the hypothalamus; hypersecretion of ACTH is a frequent cause of Cushing's Syndrome; deficiencies in ACTH can cause Addison’s disease (secondary) CORTISOL – Increase – ectopic ACTH syndrome, ectopic CRH syndrome, adrenal adenoma/ carcinoma, adrenal macronodular hyperplasia, stress, Cushing’s syndrome; Decrease – Addison’s disease, pituitary dysfunction ALDOSTERONE – used to assess adrenal aldosterone production, to diagnose primary
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