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<2.5cm cervical length (by Trans Vaginal US) greater risk of delivery <35 weeksContraction frequency alone not diagnostic of preterm laborFetal fibronectin (fFN)Glycoprotein produced by fetal tissuesCheck for presence if pt presents with s/s PTLAbsence at 20-24 weeks gestationStrong predictor no preterm birth or premature rupture of membranes in the next 2 weeksPresence at 20-34 weeks gestationPossibility of birthRequires further follow upRISKBig 3Premature ture baby in the pastPregnant with multiples (twins, triplets)Problems with cervix or uterus now or in the past (cervical insufficiency, anatomical complication)Signs/symptoms, nursing assessmentS/S (of note are similar to normal labor so always teach to call medical provider and report)Abdominal pain/contractions; menstrual crampsLow, dull backachePelvic pain/pressureVaginal bleeding/dischargeUrinary frequencyN/V/DCOMPLICATIONSystemic maturation deficiencies in the neonateTHERAPYPrimary preventionScreening for h/o PTL or S/SFetal fibronectinCervical lengthDiagnosis and treatment of infectionsCervical cerclageProgesterone injection in second trimesterPromotes uterine relaxation.Secondary PreventionTocolytic drug therapyMedication to inhibit UC
Primary goal for tocolysisDelay birth for 48 hours to maximize benefits of steroids or transport to facility with NICUSteroids: betamethasone (to increase maturation of lungs)Given 24-24 weeks12mg IM, q24 hours x2dosesDecreases likelihood of prematurity associated RDSTocolytic therapy—goal, mechanism of action of 4 major categories, nursing careBeta adrenergic agonistTerbutaline (Brethine)Mechanism: Smooth muscle relaxationRoute: IV,IM, SQ, POAdverse effects:hypotension, tachycardia, palpitations, hyperglycemiaMagnesium SulfateMechanism:displaces intracellular Calcium thus inhibits UCRoute: IV infusionAdverse effects: flushing, feeling warm, HA, nausea, drymouth, dizziness, lethargyCalcium Channel BlockerNifedipine (Procardia)*get baseline vitals)Mechanism:decreases calcium into myometrium to inhibit UCRoute:POAdverse effects:r/t arterial dilation, facial flushing, hypotension, tachycardia, HAProstaglandin Synthetase InhibitorsIndocin (Indomethacin)NSAIDRoute:POAdverse Effects:Fetal effects:oligohydramnios, premature closure of ductus arteriosis with prolonged use, not recommended after 34 weeksgestation or for longer than 48hoursCAREHealth promotion educationS/S PTLUC self evalCall provider if UC or loss of fluidHospital carePromote rest; VS; FHR with UCDecrease anxietyArrange conults inf requestedCorticosteroid therapySteroids: betamethasone (to increase maturation of lungs)Given 24-24 weeks12mg IM, q24 hours x2dosesDecreases likelihood of prematurity associated RDSPremature, Prolonged, and Preterm Premature Rupture of Membranes DefinitionRISK: bleeding/abruption, infection, prior PPROM, incompetent cervix, smokingPremature rupture (PROM)DEFINITIONSpontaneous rupture before labor onset any time AFTER 37 completed weeksProlonged ROMDEFINITION