Anthropology Sickle Cell Lab

What do you think will happen to the frequencies of

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Hypothesis/Prediction: What do you think will happen to the frequencies of the A and S alleles as a result of the presence of malaria? (Will the frequency of A increase or decrease? What about S?) Formulate a hypothesis and corresponding prediction. Be sure to explain your reasoning. Carrying the S allele in the presence of malaria results in a lower chance of death . Thus, the frequency of A will decrease and the frequency of S will increase as a result of the presence of malaria. What do you think will happen to the frequencies of the A and S alleles in a non-malarial environment? The frequencies of the A allele will increase and frequencies of the S allele will decrease in a non-malarial environment. 1
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2 Procedure: POPULATION 1: 1. Obtain four containers and label them as follows: 1) AA 2) AS 3) Non-surviving alleles 4) Gene Pool 2. Place the 75 red and 25 white beans in the Gene Pool container and mix the beans up. 3. Simulate the genetic drift that takes place at fertilization by PICKING OUT two ‘alleles’ (beans) WITHOUT LOOKING. 4. For every two beans that are chosen from the gene pool, FLIP A COIN to determine whether that individual is infected with malaria. 5. Using the table below, determine the proper container in which to put the beans. Genotype Phenotype Malaria (Heads) Not infected (Tails) A A (Red-Red) No sickle cell disease.
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