Disease of the fetus or newborn caused by trans

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disease of the fetus or newborn caused by trans placental passage of maternal antibodies against the baby’s red blood cells, resulting in red cell destruction o Usually anti-Rhesus (Rh) antibodies are involved and the disease is called Rh disease o Also called Erythroblastosis Fetalis Hives: urticarial, an allergic skin reaction characterized by the formation of itchy red swellings Hypersensitivity: also termed allergy, heightened immune response to antigen Hyposensitization: lower than normal immune response to stimuli Immunodeficiency: a state in which the body is unable to produce a normal immune response to antigen Immunotherapy: techniques used to modify the immune system action for a favorable effect Lymphocyte Deficiency: include Severe Combined Immunodeficiency Disease and DiGeorge Syndrome o Deficiency in lymphocytes Myasthenia Gravis: an autoimmune disease characterized by muscle weakness, caused by autoantibodies Rheumatoid Arthritis: severe crippling autoimmune disease in which cellular immune responses and antibodies target collagen in connective tissues, most often within joints RhuMab (Recombinant Human Monoclonal Antibody): monoclonal antibody derived from a laboratory animal in which part of the molecule has even replaced with the human equivalent Sensitization: primary exposure to an antigen that can then lead to an allergic reaction when that same antigen is encountered again Serum Sickness: systemic immune complex disease that can result from passive immunization using animal serum Severe Combined Immunodeficiency (SCID): results when hematopoietic stem cells produce neither T nor B lymphocytes children generally die of infectious disease at an early age unless they are successfully treated with bone marrow transplant Systemic Anaphylaxis: generalized allergic reaction caused by IgE, resulting in a profound drop in blood pressure Systemic Lupus Erythromatosis: a systemic autoimmune disease in which antibodies against molecules in the nuclei cause an attack against the body’s own cells Tolerance: specific unresponsiveness of the adaptive immune system that reflects its ability to ignore any given molecule such as a normal cellular protein Transfusion Reaction: reaction characterized by fever, low blood pressure, pain, nausea, and vomiting, resulting from the transfusion of immunologically incompatible blood Type I Diabetes Mellitus: organ-specific autoimmune disease caused when cytotoxic T cells destroy a certain type of pancreatic cell Xenografts: tissue graft or organ transplant from a donor of a different species from the recipient
Chapter 18 Active Immunity: protective immunity produced by an individual in response to an antigenic stimulus Adjuvant: substance that increases the immune response to an antigen Agglutination Reactions: in immunological testing, clumping together of cells or particles by antibody molecules Anti-human IgG Antibodies:

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