Below are the diagrams to demonstrate a key and lock

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Below are the diagrams to demonstrate: (a) Key and lock model of enzymatic activities
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(b) Effect of enzymes on activation energy
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The specific substrate of the enzyme aldolase B is fructose-1-phosphate. In a human body, fructose breaks down via two different metabolisms. The dominant one is in the liver and the other one is in the adipose tissue. In adipose tissue, the metabolism closely resembles that of glucose. The enzyme hexokinase act upon it to add a phosphate, which makes fructose-1-phosphate, an intermediate product of glycolysis. In liver, Fructose is phosphorylated by the enzyme fructokinase to fructose -1-phosphate. Here comes the role of aldolase B. As discussed fructose-1-phosphate is the specific substrate of aldolase B. It acts as catalyst in the reaction, during which he six-carbon fructose is then split into two three- carbon molecules, dihydroxyacetone phosphate and glyceraldehyde . Glyceraldehyde is then phosphorylated by another enzyme so that it too can enter the glycolytic pathway. CASE 2 If in some case the inter-conversions of Cori Cycle occur within one cell only, it will result into futile cycle. In this glucose is consumed and re-synthesized at the cost of ATP and GTP.
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In such a case a net loss of four ATP per cycle occurs which consequently decrease the energy reserve of the cell. Given below is the mechanism of Citric Acid Cycle: The products of Citric Acid cycle can be converted into ATP by Cori Cycle as shown below:
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Coenzyme Q10 is a vital part of the Electron Transport System (ETS) that yield ATP energy from our regular intake of food. Q10 helps to carry electrons from one molecule to another, therefore permitting for energy creation and transfer to take place succesfully. Tricyclic antidepressants, beta blockers, and phenothiazines block Q10 manufacture in the body and might worsen the condition. Coenzyme Q10 is naturally formed by the body by a process known as methylation. If methylation is spoiled in an individual, then Q10 levels may quite decrease. Coenzyme Q10, also known as Ubiquinone, is the most frequent form of supplemental Q10 coenzyme. For the people who are non-vegetarians, heart is the most concerted naturally happening nutritional resource of Q10.
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