Both and caused by m leprae and m tuberculosis

Info icon This preview shows pages 15–19. Sign up to view the full content.

View Full Document Right Arrow Icon
Both __________ and ______________, caused by M. leprae and M. tuberculosis respectively, have plagued mankind for centuries. Thought that M. tuberculosis and M. leprae evolved from a soil bacterium that infected cows, then made jump to humans about the time of animal domestication, 10,000 years ago. M. tuberculosis doubles population every 18-24 hours, M. leprae doubles population about every 14 days. Q: What might be the impact of generation time on the course of the infectious diseases these microbes cause? Images: TB Culture, Public Health Image Library ( PHIL ) #4428, Dr. George Kubica; 24 yo man from Norway, suffering from leprosy ; Pierre Arents; Acid fast stain of Mycobacteria smegmatis & Staph, T. Port Mycobacteria colonies Eewwww, looks like ear wax. Bacterial Genus : ___________ Man with Leprosy Acid-fast stain The pink is our lab friend Mycobacterium smegmatis From the Virtual Microbiology Classroom on ScienceProfOnline.com
Image of page 15

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Mycobacterial Cell Wall Image: Mycobacterial cell wall , Ytambe 1. outer lipids 2. mycolic acid 3. polysaccharides 4. peptidoglycan 5. plasma membrane 6 & 7: Molecules involved in evading host immune cells & function. 8. cell wall Because of waxy cell wall, they can survive exposure to acids, alkalis, detergents, oxidative bursts, lysis by immune system, and many antibiotics. From the Virtual Microbiology Classroom on ScienceProfOnline.com
Image of page 16
Bacterial Genera: _________ & __________ GRAM NEGATIVE Non-lactose fermenters Facultative anaerobes , bacillus-shaped Food poisoning: Infection in lining of small intestine caused by bacteria (both G+ & G- ), including Salmonella and Shigella . Transmission: Ingesting foods and materials that are fecally contaminated. Symptoms / Course: Diarrhea, fever, and abdominal cramps 12 - 72 hours after infection. Usually lasts 4 to 7 days . Most recover without treatment. Severe infections may last several weeks . Bacteria shed in feces. Carrier state exists in some people who shed the bacteria for 1 year or more following initial infection. Treatment: Replace fluids. Don’t use anti-diarrheals. May prolong illness. Thorough cooking kills these bacteria. Proper food handling, storage and good hand washing are preventive measures. Images: MacConkey’s media , one growing Salmonella, the ther E. coli (lactose fermenter); Food poisoning diagram , Shirley Owens, Michigan State University MacConkey’s NON- Lactose Fermenter From the Virtual Microbiology Classroom on ScienceProfOnline.com
Image of page 17

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
GRAM NEGATIVE Bacteria Lactose fermenters Facultative anaerobes, bacillus-shaped CAUSE: Bacteria, usually E. coli , in urinary tract. More common in women due to short urethra and proximity to anus. Bacteria must be able to “stick” to cause infection (otherwise bacteria would just get peed out). Bladder lined with proteins, to prevent this. E. coli has fimbriae to help it stick. SYMPTOMS: Pain and tenderness in the genital region; burning and itching with urination.
Image of page 18
Image of page 19
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern