13 nasal allergies granules full of histamine

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13 Nasal Allergies Granules, full of histamine Degranulation, histamine release Y Allergens Mast Cell Hay Fever Indoor IgE Antibody Sneezing Runny nose Outdoor
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14 Allergic Responses
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15 Understanding Allergies movie
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16 Midterm 1 will be next week Thursday April 25th Lectures 1 to 6 Multiple choice True / False Short answer Scantron
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17 Please bring a BLUE scantron to the midterm
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18 Lecture 6: Immunology, cont’d 1. Cells of the immune system 2. Phagocytosis 3. Major Histocompatability complex 4. Cell-mediated immunity 4/18/2013
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19 Role of the Bone Marrow Marrow Red blood cells White blood cells Platelets Committed Precursor Cells Stem Cells Hematopoietic stem cell
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20 Hematopoiesis
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21
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22 White Blood Cells Lymphocytes: T Lymphocytes B Lymphocytes Natural Killer Cells Granulocytes: Monocytes Mast Cells Neutrophils Macrophages Dendritic cells
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23 White Blood cells
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24 Nerve Ending Bacteria Mast Cell Monocytes Macrophage Neutrophil Tissues Blood clots wall off capillary, preventing blood loss Histamine Inflammatory Reaction Phagocytosis
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25 Communication Molecules • Cytokines are soluble proteins that promote immune responses. Many are involved in inflammatory reactions. Examples = lymphokines, interleukins, interferons
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26 A specific form of endocytosis involving the vesicular internalization of solid particles, such as bacteria In the immune system it is a major mechanism used to remove pathogens and cell debris Phagocytosis Major phagocytic cells of the immune system - Neutrophils - Macrophages - Dendritic cells
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27 Respiratory or oxidative burst
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28 Macrophages and Phagocytosis Phagocytosis of bacteria not coated with antibody Phagocytosis of bacteria coated with antibody is much more efficient
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29 Antibody opsonization is the process by which a pathogen is marked for ingestion and destruction by a phagocyte Fc receptor
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