Copyright 2017 wolters kluwer all rights reserved

Copyright © 2017 Wolters Kluwer • All Rights Reserved
Dermatological Reactions
Dermatological Reactions
•
Rash/Hives
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Assessment
•
Abnormalities in the skin, red area, blisters
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Interventions
•
May need to discontinue the medication in severe cases
•
Stomatitis
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Assessment
•
Inflammation of the mucous membranes
–
Interventions
•
Frequent mouth care

Copyright © 2017 Wolters Kluwer • All Rights Reserved
Drug-Induced Tissue and Organ Damage
Drug-Induced Tissue and Organ Damage
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Superinfections — Destruction of the body’ s normal flora
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Assessment
•
Fever, diarrhea, vaginal discharge
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Interventions
•
Supportive care (mouth and skin care), administer antifungal
medications as needed, may also need to stop drug
responsible for the superinfection
•
Blood Dyscrasia — Bone marrow suppression
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Assessment
•
Fever, chills, weakness
–
Interventions
•
Monitor blood counts, protective isolation

Copyright © 2017 Wolters Kluwer • All Rights Reserved
Toxicity
Toxicity
Affecting the body in a very noxious or toxic way
•
Liver- Assessment
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Fever, nausea, jaundice, change in color of urine or stool,
elevated liver enzymes
–
Interventions
• Discontinue medication
•
Kidney- Assessment
•
Change in urinary pattern, elevated BUN and creatinine
–
Intervention
•
Notify physician, may need to stop medication or decrease the
dosage

Copyright © 2017 Wolters Kluwer • All Rights Reserved
Poisoning
Poisoning
•
Poisoning occurs when an overdose of a drug damages
multiple body systems.
•
Damage to multiple systems can lead to a fatal reaction.
•
Treatment varies accordingly with drug

Copyright © 2017 Wolters Kluwer • All Rights Reserved
Altered Glucose Metabolism
Altered Glucose Metabolism
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Hypoglycemia
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Assessment Finding: Low serum blood glucose level
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Intervention: Restore glucose to the body
•
Hyperglycemia
–
Assessment Finding: High serum glucose level
–
Intervention: Administer medications to decrease
glucose level

Copyright © 2017 Wolters Kluwer • All Rights Reserved
Electrolyte Imbalance
Electrolyte Imbalance
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Hypokalemia
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Assessment Finding: Decrease in serum potassium levels
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Interventions: Replace serum potassium (IV or oral
supplement) and monitor serum levels of potassium
•
Hyperkalemia
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Assessment Finding: Increase in serum potassium level
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Interventions: Decrease the serum potassium
concentration (Sodium Polystyrene Sulfonate), monitor
serum levels of potassium, and monitor cardiac rhythm

Copyright © 2017 Wolters Kluwer • All Rights Reserved
Sensory Effects
Sensory Effects
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Ocular Toxicity
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Assessment Findings: Visual changes
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Interventions: Monitor for any visual changes when giving
any medication that is known to cause ocular damage;
discontinue medication as appropriate.