The therapeutic drug used to treat all but absence seizures by prolonging

The therapeutic drug used to treat all but absence

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142.The therapeutic drug used to treat all but absence seizures by prolonging inactivation of the synaptic sodium channel and reducing synaptic transmission is:143.What is occurring in phase I metabolism of a therapeutic drug?144.What therapeutic drugs is considered to be a selective serotonin reuptake inhibitor?145.A class III antiarrhythmic drug that acts by blocking potassium channels and that is used to manage atrial fibrillation is:146.What therapeutic drugs is used in the management of acute lymphoblastic leukemia and inhibits DNA synthesis bydecreasing methylation of pyrimidine nucleotides and their synthesis?147.What is nota good rationale for monitoring the blood concentration of a therapeutic drug?148.Mycophenolate mofetil (MMF) is rapidly hydrolyzed by widely distributed esterases in blood and tissue to produceMPA. In regard to drug metabolism, this chemical reaction isreferred to as:149.The method of monitoring therapeutic drug concentrations that is replacing HPLC-based methods and is now considered to be the best technology for analysis of biological specimens with high specificity and fewer interferences is:150.For a therapeutic drug that has a short half-life, for example levetiracetam, when is the appropriate time to collect a blood sample for therapeutic drug assessment?151.The name given to the group of enzymes that are particularly involved in phase I metabolism of drugs and thatinvolve reduction/oxidation or hydrolysis is:152. An individual who appears to be very inebriated is brought to a hospital emergency department by the police. Laboratory blood gas results indicate metabolic acidosis withan increased serum osmol gap, the presence of serum acetone, and many urine oxalate crystals. Which alcohol did this individual ingest?153.What is the major metabolite of acetaminophen that is formed in the liver?11
Chem TB Flashcards Unit 3154.) In a clinical laboratory without gas chromatography instrumentation, the common method of choice used to measure ethanol in serum or plasma is a(n):

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