Most afferents terminate in external granular and internal granular o Most

Most afferents terminate in external granular and

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Most afferents terminate in external granular and internal granular o Most   efferents   arise   from  external  granular,   external  pyramidal,   and  internal pyramidal  o Multiform projects to thalamus  Vertical columnar:   Cytoarchitecture/”chunks”, functional organization (homunculus) o Divergent pathways o Good for parallel processing o Column size is experience dependent; changes with injury and learning Implications:  Projections classifications: ( page 244&245) Subcortical (projection fibers) impulses to and fro subcortical areas (thalamus, brain stem, spinal cord) Association :  connect neurons within a hemisphere  o Ex:  synergist share “rich” connections. 4 muscles in quad—they share the rich connection 
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Commissural:  connect neurons to the contralateral hemisphere o Ex: corpus collosm and commissures
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Development Cell migration: In to out (layer 6/VI  migrate first) o Works from inner most layer to the outer most layer Thalamic sensory neurons attach to cortical neurons o Sensory + motor =  sensorimotor integration o Dependent  on genetic factors Complete before birth Neural Exuberance:  “all over the place”; projections to many areas Pro: redundancy Con: lacks precision  Critical periods:  an immature state of neural areas or projections transformation: Regressive Events Cell death—we lose about 50% of neurons during development Axonal retraction Synptaic retraction = pruning – effective synapses  ***Activity***
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  • Spring '14
  • HONDZINSKI
  • Pyramidal cell, pyramidal neurons, large pyramidal neurons, pack granular neurons

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