Re try in 19534 success of potassium bromide they

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Re . try in 19534 success of potassium Bromide . They found a 2 eduction Of seizures which is not amazing d. effects on patients - 1878 , frenchmen Seguin had a better trial Wh had one group with placebos and had a 20% reduction 4 Lithium 4 bipolar disorder - as they Used it more they found limitations , 23 . sing bromides could get a long term remission but a. Language to use in 18905 40% have about no effect b . John code : Guinea pigs hpatients 1864 , synthesized Barbiturates c. Denmark Mogen school - came up With a Phenobarbital , Which Was in 1902 Is et was used as a sedative d. 1960 A new toolkit - first tried out for epileptic patients in 1912 , so a last resort - found that phenobarbital lessened the frequency are rity . Worked on cases that me refractory to bromides . spread in the post World War pevro . its biggest Problem Was that it was sedative . Reduced symptoms but created a unique lifestyle Dilantin , 19305 - two harvard doctors , Tracy Puthum and Huston Merrit - developed an experimental produce we to test the drugs on cats . Used artificial seizure ( then they could test the dny on animal models - first xwti - convulsive . . . could differentiate where it worked best - 1940 , drd a study with 118 Patients , had an array of seizures found 581 . effective . Eliminated Grand Mal seizures . Reduced the frequency in 27 't it controlled seines without being a sedative . 19405 , psychiatry 1 - dominance of Freud disappeared due to medicine - We see better understanding of " mental illnesses , " epileptics No longer associated with lunatics . mental effects of substance abuse came to be better understood - Walking wounded the anxious patients / those with anxiety and various forms of Unhappiness - schizophrenia not someone Who has different personalities by 1940 , , two different sides of schizophrenia , could be psychosis . But they Key Computent hehe is ( positive ) hallucinations . a great deal of hallucinations are auditory Characterized by illogical thinking negative side not very uommunatine , they just sit them , sometimes frozen . - second problem , major depression refers to a low mood , diminished Interest in pleasure . Had to last at least 6 months . often weight loss or Weight gain , often either insomnia or excessive sleeping . 4 exhibiting of retardation . slower ability to think
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Outline ' . Notes : I cont from last page ) 11 1 Pyschiatry in the 19405 - manic depressive " a. Dominance of Freud person cycles DIW high mood and low Mlvd . Capable ot different Variations . Bipolar b. Exclusions + walking wounded When it gets to the bipolar stage , people are sent to mental hospitals , which lead to overcrowded Mental hospitals c. Schizophrenia The first Anti - psychotics 2 d. Depression - 18505 , 1st synthetic dye discovered e. " Manic depressive " - 1883 , BASF had synthesized Phenothixzme . wasn't really used until WWTI f.
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