WBC counts:
Normally, a cubic milliliter of blood contains between
__5,000
______ & __
10,000___
white blood cells. A __
differential_________
white blood cell count can help
pinpoint the nature of an illness, indicating whether it is caused by bacteria or viruses.
Acute infections cause an excess of WBCs known as _leucocytosis__________.
A deficiency of WBCs, called _____
leucopenia_____,
can also indicate a variety of infections
including AIDS.
What is leukemia?
A malignant progressive disease in which the bone marrow and other blood-
forming organs produce increased numbers of immature or abnormal leukocytes. These suppress the
production of normal blood cells, leading to anemia and other symptoms
Granulocytes
:
Why is this group called granulocytes?
Because they have granules in the cytoplasm.
Neutrophils:
Neutrophils have ___
red
________-staining fine cytoplasmic granules and a __
multi
____-lobed
nucleus; they comprise most of the leukocytes.
What is their function?
Phagocytize bacteria, fungi, and some viruses.
What does diapedesis mean?
Squeezing between cells in blood vessel walls.
4

Eosinophils:
Eosinophils have coarse granules that stain deep
a ___
bi
_______-lobed nucleus.
What are their functions?
Moderate allergic reactions, defend against certain parasites.
Basophils:
Basophils have fewer granules that stain ___
deep blue
______________.
Basophils produce chemicals, what are the functions of these chemicals?
(i)
heparin-
increase blood flow to damaged tissues
.
(ii)
histamine-
Promote inflammation response
Agranulocytes
:
Why are they called agranulocytes?
They do not have cytoplasmic granules
Monocytes:
Monocytes are the ____
largest
_________ blood cells, have ____
oval
__________-shaped nuclei.
What is the function of the monocytes?
The main function of monocytes is to ingest harmful, dead, or damaged cells in the blood.
Lymphocytes:
Lymphocytes are long-lived, have a large, ___
spherical
________ nucleus.
What is their function?
They are involved in immunity responses.
Platelets
= thrombocytes
:
Blood platelets are fragments of big cells called ____
megakaryocytes
_____________________.
Platelets help repair damaged blood vessels by ______
adhering
__________ to their broken edges.
Plasma:
Plasma is the clear, straw-colored fluid portion of the blood.
5

What are plasma’s functions?
Plasma functions to transport nutrients and gases, regulate fluid and electrolyte
balance, and maintain a favorable pH.
Plasma proteins:
The plasma proteins are the most abundant dissolved substances in the plasma
.
Briefly describe the functions of the following plasma proteins.
albumin
: Help maintain the osmotic pressure of the blood and
account for 60% of the plasma proteins.
globulin:
Are designated as alpha, beta, and gamma globulins. Alpha and beta globulins
function in transporting lipids and fat soluble vitamins. Gamma globulins are a type of
antibody
fibrinogen:
Plays a primary role in blood coagulation.
hormones:
Peptides regulate functions such as sleep and sugar concentration. They are
made from long strings of amino acids, so sometimes they are referred to as "protein"
hormones.


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- Winter '14
- red blood cells