Urinary Incontinence Pathophys I Fall 2012 STUDENT (1)

Intra abdominal pressure coughing laughing sneezing

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intra-abdominal pressure Coughing Laughing Sneezing Increased exertion Urethral sphincter is not able to resist the flow of urine Small amount of urine is lost
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Stress Urinary Incontinence (SUI) (Urethral Underactivity) Risk factors: Pregnancy Childbirth Menopause Cognitive impairment Obesity Age
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Stress Urinary Incontinence (SUI) (Urethral Underactivity) Intrinsic urethral deficiency Due to congenital sphincter weakness Acquired from Trauma Irradiation Males Uncommon Due to lower urinary tract surgery Prostatectomy
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Stress Urinary Incontinence
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Urge Urinary Incontinence (Bladder Overactivity) Involuntary loss of urine associated with urgency Usually loss of a large amount of urine Detrusor muscle contracts improperly during filling phase Overactive bladder Clinical syndrome of urgency, frequency, dysuria, nocturia With or WITHOUT incontinence
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Urge Urinary Incontinence (Bladder Overactivity) Neurogenic causes Damage to central inhibitory pathways Muscarinic receptors are constantly being stimulated Acetylcholine Sensitization of peripheral afferent terminals in the bladder Increased peripheral afferent activity Increased peripheral sensitivity to efferent impulses
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Urge Urinary Incontinence (Bladder Overactivity) Myogenic causes Changes in bladder pressure due to changes
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