Enzymes in the liver and kidneys transform that

Info icon This preview shows pages 30–36. Sign up to view the full content.

View Full Document Right Arrow Icon
Enzymes in the liver and kidneys transform that molecule into calcitriol (most active form of vitamin D) Necessary vitamin for absorption of calcium from food in the gastrointestinal tract
Image of page 30

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Transdermal Drug Administration Method by which drugs in a patch enter the body Drug absorption most rapid in areas where skin is thin (scrotum, face and scalp) Examples nitroglycerin (prevention of chest pain from coronary artery disease) estradiol (estrogen replacement therapy) nicotine (stop smoking alternative)
Image of page 31
Age Related Structural Changes Collagen fibers decrease in number & stiffen Elastic fibers become less elastic Fibroblasts decrease in number Langerhans cells and macrophages decrease in number and become less-efficient phagocytes Oil glands shrink and the skin becomes dry Walls of blood vessels in dermis thicken so decreased nutrient availability leads to thinner skin as subcutaneous fat is lost
Image of page 32

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Photodamage Ultraviolet light (UVA and UVB) both damage the skin Acute overexposure causes sunburn DNA damage in epidermal cells can lead to skin cancer UVA produces oxygen free radicals that damage collagen and elastic fibers and lead to wrinkling of the skin
Image of page 33
Burns Destruction of proteins of the skin chemicals, electricity, heat Problems that result shock due to water, plasma and plasma protein loss circulatory & kidney problems from loss of plasma bacterial infection
Image of page 34

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Types of Burns First-degree only epidermis (sunburn) Second-degree burn destroys entire epidermis & part of dermis fluid-filled blisters separate epidermis & dermis epidermal derivatives are not damaged heals without grafting in 3 to 4 weeks & may scar Third-degree or full-thickness destroy epidermis, dermis & epidermal derivatives damaged area is numb due to loss of sensory nerves
Image of page 35
Pressure Sores Decubitus ulcers Caused by constant deficiency of blood flow to tissue Areas affected is skin over bony prominence in bedridden patients Preventable with proper care
Image of page 36
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern