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PracticeExam5

Which compound below is an intermediate of oxidation

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22. Which compound below is an intermediate of $ oxidation: 3 2 20 3 2 2 3 3 2 2 a. CH -(CH ) -CO-COOH. b. CH -CH -CO-CH -COOPO . c. CH -CH -CO-CH OH = 3 2 3 2 2 d. CH -CH -CO-CO-S-CoA e. CH -CH -CO-CH -CO-S-CoA. 23. Which of the following is a zymogen that can be converted to an endopeptidase that hydrolyzes peptide bonds adjacent to Lys and Arg residues? 24. Which of these directly donates a nitrogen atom for the formation of urea during the urea cycle? 25. Conversion of ornithine to citrulline is a step in the synthesis of: 26. Which of the following statements is false in reference to the mammalian synthesis of urea? a. Krebs was a major contributor to the elucidation of the pathway involved.
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b. The amino acid arginine is the immediate precursor to urea. 3 c. The carbon atom of urea is derived from mitochondrial HCO - d. The precursor to one of the nitrogens of urea is aspartate. e. The process of urea production is an energy-yielding series of reactions. 27. The human genetic disease phenylketonuria (PKU) can result from: 28. Which substance is not involved in the production of urea from NH4 via the urea cycle? + 29. Amino acid catabolism takes place in the: 30. Urea synthesis in mammals takes place primarily in tissues of the: a. brain . b. kidney. c. liver. d. skeletal muscle. e. all of these. Written Answer Questions 1. For the average adult (70 kg or 154 lb), 15% of the body is fat. a. Calculate the energy reserve in terms of kJ. Assume 38 kJ/gram fat. (5points) b. Our 70 kg human consumes roughly 8,400 kJ/day (which is 2,000 kcal/day or 2,000 dietary cal/day). Clicker Question: How long could this person survive on their fat reserves? (5 points). 2. A new manufacturer of IV saline+glucose solutions got into trouble for mixing up the proportions of saline (normally 0.9% as NaCl ) and glucose (normally 5%). What was the actual glucose concentration in mM of this unfortunate IV product? The molecular weight of glucose is 180 Daltons. (10 points).
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3. The malate dehyrogenase reaction has a ) G ’ of 29 kJ/mole. In most mitochondrial prepartions the ratio of o [NAD ]/[NADH] is 10 and the [malate] is 0.2 mM. Calculate the concentration of oxaloacetate. (10 ponts). +
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