83 o ATP is the cells energy shuttle Hydrolysis of its terminal phosphate

83 o atp is the cells energy shuttle hydrolysis of

This preview shows page 1 - 2 out of 2 pages.

8.3: o ATP is the cell’s energy shuttle. Hydrolysis of its terminal phosphate yields ADP and (P) i and releases free energy. o Through energy coupling , the exergonic process of ATP hydrolysis drives endergonic reactions by transfer of a phosphate group to specific reactants, forming a phosphorylated intermediate that is more reactive. ATP hydrolysis (sometimes with
Image of page 1

Subscribe to view the full document.

protein phosphorylation) also causes changes in the shape and binding affinities of transport and motor proteins. o Catabolic pathways drive regeneration of ATP from ADP+(P) i . 8.4: o In a chemical reaction, the energy necessary to break the bonds of the reactants is the activation energy , E A . o Enzymes lower the E A barrier. o Each enzyme has a unique active site that binds one or more substrate(s) , the reactants on which it acts. It then changes shape, binding the substrate(s) more tightly ( induced fit ). o The active site can lower an E A barrier by orienting substrates correctly, straining their bonds, providing a favorable microenvironment, or even covalently bonding with the substrate. o Each enzyme has an optimal temperature and pH. Inhibitors reduce enzyme function. A competitive inhibitor binds to the active site, whereas a noncompetitive inhibitor binds to a different site on the enzyme. o Natural selection, acting on organisms with variant enzymes, is responsible for the diversity of enzymes found in organisms. 8.5: o 1)
Image of page 2
  • Spring '19

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern

Ask Expert Tutors You can ask You can ask ( soon) You can ask (will expire )
Answers in as fast as 15 minutes