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8 e bier the coiled spring how life begins cold

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E. Bier, The Coiled Spring: How Life Begins , Cold Spring Harbor Labora- tory Press, 2000. I really enjoyed reading this book on developmental biology - this is a fascinating area full of beautiful problems. The idea being explored is that all animals have more or less the same genes and yet they turn out very differently. We turn out so differently because different decisions are made about when and where to turn these genes on. I should note that before I got to the end I was overwhelmed by nomenclature that I have not yet mastered. I will definitely try this one again soon. J. Israelachvili, Intermolecular and Surface Forces , Academic Press, 1992. The subject of this book is much larger than is implied by the title. We will make reference to Israelachvili’s discussion both when discussing forces in the material world and also in the context of self-assembly. C. R. Calladine and H. R. Drew, Understanding DNA , Academic Press, 1999. This book provides a window on DNA which makes a good deal of contact with the perspective that will be brought to this important molecule in the course. M. Doi, Introduction to Polymer Physics , Oxford University Press, 1996. this book is short and sweet and provides a readable introduction to many of the ideas from polymer physics that we will borrow in our attempt to understand the mechanics of biological macromolecules. P.-G. de Gennes, Scaling Concepts in Polymer Physics , Cornell University Press, 1979. de Gennes classic epitomizes the appeal of “universal” insights, especially as practiced by a master. A. Y. Grosberg and A. R. Khokhlov, Giant Molecules , Academic Press, 1997. A very nice introduction to the physics of macromolecules. Describes many of the arguments that will be made in our course. U. Seifert, Configurations of fluid membranes and vesicles , Adv. Phys., 46 , 13 (1997). Seifert provides a detailed description of the elasticity of 9
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membranes as well as insights into the current understanding of equilibrium shapes. H. C. Berg, Random Walks in Biology , Princeton University Press, 1993. A must read. Berg has all sorts of fun and interesting things to say. I would hold this book up as another example of a book of the highest quality built around simple ideas applied in a thoughtful manner to important problems (like Ptashne, Klotz, de Gennes and some of the others on this list). M. Doi and S. F. Edwards, The Theory of Polymer Dynamics , Clarendon Press, 1986. Doi and Edwards have some important discussions of the mo- tion of polymers in crowded environments. H. Echols, Operators and Promoters and H. F. Judson, The Eighth Day of Creation . I round out the list with these two very interesting books on the history of molecular biology. Judson’s book is one of my three all time fa- vorite scientific biographies and is instructive both on the science and on the types of personalities that did that science. Echols was a molecular biologist himself and tells the story of the development of molecular biology in very compelling terms - if you read this book you will learn much biology. 10
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8 E Bier The Coiled Spring How Life Begins Cold Spring...

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