Labs ELISA determines antibodies for HIV antigen testing CD4 T cell count

Labs elisa determines antibodies for hiv antigen

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Labs: ELISA determines antibodies for HIV, antigen testing, CD4+ T cell countProtease inhibitors, nucleoside reverse transcriptase inhibitors, nonnucleoside reverse transcriptase inhibitors, immunomodulatory drugs to boost weakness immune system, anti-infective and anti-neoplastic drugsoNursing Dx: Risk for infection; Ineffective coping; Impaired skin integrity; Imbalanced nutrition: less; anxiety; fear; deficient knowledgeoNursing intervention/implications: Standard precautions, cardiopulmonary status, report cough/sore throat/adventitious sounds; monitor for fever; assess for tender swollen lymph nodes, provide mouth care; monitor nutritional status; prevent secondary infection; maintain skin integrityoEducation: support for family and patient; promote adherence to medication regiment; address ineffective sexuality patternsITP, TTP, HIT (1-2 questions)oITP:Bleeding disorder in which blood doesn’t clot as it should due to a low number of platelets; immune systems attacks and destroys its own plateletsNormal platelet count: 150.000-450,000/ µLCan be linked to viral or bacterial infections such as HIV, hepatitis C or H. pyloriChildren often have had recent viral infectionsBleeding can occur inside the body or underneath of from the skin (external bleeding)S/S: Purpura on skin or mucous membranes, petechial, hematoma, nosebleeds or bleeding from the gums, blood in urine or stoolDiagnosis: medical history, physical exam, labs: CBC, blood smear, antibodies that attack plateletsTreatment: Corticosteroids to increase platelet count, rituximab, immune globulin, anti-Rh (D) immunoglobulin; splenectomy (spleen makes antibodies to help fight infections which are destroying platelets by mistake)Platelet transfusions, treating infections, stopping medications that lower platelet count or cause bleeding (aspirin, ibuprofen)IV Rho(D): 50-77% of pts achieve platelet response; Adverse effects= headache, fever, chillsIV Ig: effective in >80% of patients; Adverse effects= severe headache, feverPrednisone: up to 75% pts will respond depending on dose; Adverse effects= transient mood changes, gastritis, weight gain, exercise caution in active infectionWatch/wait: approximately 66% will spontaneously improve within 6 months; Adverse effects= hemorrhage (preventable), anxietyEducation: lifestyle changes (avoiding injuries, safe activities), ongoing care, during pregnancy (more likely to have heavy bleeding during delivery and afterward)oTTP:Rare blood disorder in which blood clots form in small blood vessels throughout the body; clots can limit or block flow of O2 rich blood to body’s organs; autoimmune disorder
Villani 6Lack of activity in ADAMTS13 enzyme (protein in the blood) causes TTP- controls enzyme involved in blood clotting and breaks up von Willebrand factor that clumps together with platelets to form blood clotsTypesInherited- mainly affects newborns and childrenAcquired- more common, develop the disorder, mostly in adults; ADAMTS13 gene not faulty but

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