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Everyday activities like cleaning cooking climbing

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Everyday activities like cleaning, cooking, climbing stairs, and getting upfrom a chair become difficult. Falls become more likely, which raises therisk of painful, debilitating bone fractures.HSS1101 Health through physical fitness56
Inactivity raises the risk of chronic conditions.Compared to their exercising peers, inactive people aged 30to 69 increase their risk of heart attack by nearly 100percent, colon cancer by 80 percent, type 2 diabetes by 76percent, and stroke by 72 percent. In women, breast cancerrisk rises 56 percent.[6]Obesity and depression also becomemore likely.Inactivity is expensive.If you were concerned about theprice of a pair of running shoes, consider the costs of sittingaround, which raises the risk of many chronic conditions—conditions that become increasingly expensive to treat.One analysis showed that physical inactivity, combined withoverweight and obesity, accounted for 27 percent ofnational health care charges.[HSS1101 Health through physical fitness57
Anabolic Steroids (AS)AS are responsible for increased skeletal muscle proteinsynthesis and hypertrophy, decreased rates of proteincatabolism, satellite cell activation without proliferation, apositivenitrogenbalance,stimulatingerythropoietinsynthesis, and increasing androgen receptors.AdverseEffects: the long term effects of AS need to bestudied but to date, the known effects of using AS has beendivided into five general categories1.hepatic (liver related)2.cardiovascular3.dermatological4.reproductive/endocrine5.psychiatricHSS1101 Health through physical fitness58
Adverse Effects of ASHepatic:increased liver enzymes that can lead tojaundice.Levels return to normal in the absence ofAS which is one of the reasons AS are taken in cycles.Liver cancer has also been associated with AS use.Cardiodvascular:AS lead to changes in serum lipidprofile by increasing LDLs, decreasing HDLs, andincreased total cholesterol.Hypertension is alsoassociated with AS probably from increases in bloodvolume and fluid retention.Dermatological:AS have been shown to cause acne,oily skin, oily hair, hypertrophy of sebacious glands,and alopecia.HSS1101 Health through physical fitness59
Adverse Effects of ASReproductive/Endocrine:AS creates a negative feedback loop thatreduces luteinising hormone (LH) and follicle-stimulating hormone.These hormones are required for spermatogenesis; thus leading todecreased sperm density, count, mortality, morphology, testicularatrophy, without change in libido.Compensated by chorionic gonadotropin to stimulate LH and testicular testosteroneproduction.Testosterone can be converted to estrogen leading to the feminisation ofmen which is characterized by voice pitch and gynaecomastia.

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Term
Spring
Professor
GOMES
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