E55-2009 practice exam 2

The graft is associated with a new somite boundary

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electroporated with activated Notch ligand, then placed into a host PM. The graft is associated with a new somite boundary later in development. What does this result show? A. Notch signaling is necessary for in somite formation B. Notch signaling is sufficient to induce somite formation C. correlative data that Notch functions in somite formation D. both B and C E. none of the above are accurate ______9. Somite identity and pattern formation along the A/P axis is influenced by: A. signals from the organizer B. signals from the ventral mesoderm C. nested domains of Hox gene expression D. Notch signaling during somitogenesis E. secretion of Shh by the spinal cord floor plate ______10. Which pathway(s) relies on elevation of B-catenin to transduce its signals? A. Notch signaling B. TGFB signaling C. Wnt signaling D. Hox gene signaling E. both B and C ______11. Neurulation is an example of which of the following morphogenetic movements? A. ingression B. invagination C. epiboly D. convergent extension E. delamination ______12. You mate a wild-type male fly to a homozygous mutant gurken/gurken female fly. Of the following, which phenotype might you reasonably expect to obtain in the progeny? A. the embryos will develop normally B. the embryos will be dorsalized C. the embryos will be ventralized D. the oocytes will be infertile E. half the embryos will be normal, and half will be dorsalized ______13. The cleavage plane during cytokinesis is set by: A. spindle microtubules B. astral microtubules C. positions of the newly-formed nuclei D. both B and C E. none of the above ______14. Induction of intermediate mesoderm requires a signal(s) from: A. the prechordal plate B. the archenteron C. the organizer D. the paraxial mesoderm E. none of the above
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E-55, Exam 2-2009: Name Page 4 of 9 ______15. Determination of dorsal ectoderm to become neural rather than epidermal requires: A. BMP signals from the organizer B. BMP antagonist signals from the organizer C. BMP antagonist signals from the ventral mesoderm D. BMP signals from the ventral mesoderm E. maternally supplied Nodal signals ______16. You are working to investigate cytokinesis in a newly discovered marine invertebrate. You generate antibodies to conserved proteins involved in cell division in other organisms to search for proteins that localize to important structures during cell division. What molecules should you look for in the contractile ring? A. tubulin B. actin C. myosin D. both A and B E. both B and C ______17. Muscle cells A. derive from the intermediate mesoderm B. emerge from the somite sclerotome C. emerge from the somite dermatome D. fuse during the process of differentiation E. can be converted to cartilage by endochondral ossification ______18. Which of the following signaling pathways can only occur via juxtracrine activity? A. Wnt B. TGFB C. Notch D. BMP E. none of the above ______19. The metanephric kidney arises from the: A. paraxial mesoderm B. chordamesoderm C. lateral plate mesoderm D. intermediate mesoderm E. prechordal plate ______20. Somites are comprised of mesoderm precursors that generate: A. bone B. tendons C. dermis D. muscle E. all of the above
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E-55, Exam 2-2009: Name Page 5 of 9 Short answer (point values indicated) . Provide a concise response in the space provided.
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The graft is associated with a new somite boundary later in...

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