- “golden potato” has been genetically modified such as the golden rice. Not on the market yet. Can give enough vitamin A. - Why not distribute supplements or grow carrots or sweet potatoes? Difficult for people to get them to take a supplement everyday or carrots and sweet potatoes are not part of their diet which are foreign food for them. Better approach to improve their food which they take daily. - One concern with beta carotene: beta carotene supplements in smokers have been shown to increase the risk of lung cancer in the 1990s. Only smokers who take large doses of beta carotene. It is an antioxidant and they thought it could reduce the risk, but that was 18
not the case. Cannot overdose on beta carotene unless you are a smoker. While beta- carotene is safe, it is possible to overdose on vitamin A. An excess of beta carotene can cause your palms to turn orange but nothing worse = Carrot anemia. However, overdosing on preform vitamin A from animal. For example: polar bear liver is so toxic that it has killed people because of the high concentration of vitamin A. - Nobody should exceed 10 000IU a day of vitamin A. 4000-5000 IU a day is good. - Tretinoin = treatment of skin disease. Not a form of retinoid acid found in food. This is made in laboratory, but it can have a dramatic effect of acne. Retin-A cream can be applied topically and effective. - Taken internally = accutane (isotretinoin). However, a drug that cannot be taken with pregnancy and can affect the embryo. They have to make sure that the woman needs to use a birth control because the risk is significant. Video 2 In 1921 Dr. Elmer Mccollum discovered Vitamin D . Discovered that it could prevent a disease known as rickets which is a malformation of the bones. During industrial revolution in the 1850s when children were forced to work in the mines where there was no sunshine and the sky was filled with smoke. This resulted in rickets. Cod liver oil could treat rickets. Vitamin D = the sunshine vitamin. The sun is a form of radiation so it cannot contain Vitamin D, but it can trigger chemical reactions in the body by which vitamin D is formed. Precursors in the body that when exposed to sunlight will unleash a cascade of reactions that cause formation of vitamin D. Lack of vitamin D causes rickets and weak bones (osteoporosis) Milk and dairy products are supplemented with milk to prevent osteoporosis and breaking of bones. 100IU/250 mL glass of milk and that is plenty. Many claims of benefits for vitamin D: - Reduces respiratory tract infections such as the cold. Research shows that there is no evidence for this. - Improve depression and mental well-being. Research shows no evidence - Prevent or treat rheumatoid arthritis: No evidence - Treat multiple sclerosis: No evidence. - Reduce mortality over the period study. Effects are not consistently statistically significant.
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- The Bible, Vitamin