What is the function of topoisomerase a relieving

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47) What is the function of topoisomerase? A) relieving strain in the DNA ahead of the replication fork B) elongation of new DNA at a replication fork by addition of nucleotides to the existing chain C) the addition of methyl groups to bases of DNA D) unwinding of the double helix E) stabilizing single-stranded DNA at the replication fork Answer: A Topic: Concept 16.2 Skill: Knowledge/Comprehension 48) What is the role of DNA ligase in the elongation of the lagging strand during DNA replication? 49) Which of the following help to hold the DNA strands apart while they are being replicated? 13
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50) Individuals with the disorder xeroderma pigmentosum are hypersensitive to sunlight. This occurs because their cells have which impaired ability? 51) Which would you expect of a eukaryotic cell lacking telomerase? A) a high probability of becoming cancerous B) production of Okazaki fragments C) inability to repair thymine dimers D) a reduction in chromosome length E) high sensitivity to sunlight Answer: D Topic: Concept 16.2 Skill: Application/Analysis 52) Which of the following sets of materials are required by both eukaryotes and prokaryotes for replication? 53) A typical bacterial chromosome has ~4.6 million nucleotides. This supports approximately how many genes? 14
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54) Studies of nucleosomes have shown that histones (except H1) exist in each nucleosome as two kinds of tetramers: one of 2 H2A molecules and 2 H2B molecules, and the other as 2 H3 and 2 H4 molecules. Which of the following is supported by this data?
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