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34 in patients at particularly elevated risk testing

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[34]Inpatients at particularly elevated risk, testing before 30 years of age may be indicated. Patients who initially testnegative for diabetes should be periodically reassessed throughout their lifetime.Patients with PCOS are also at an increased risk for endometrial hyperplasia and carcinoma.[4, 35]The chronicanovulation in PCOS leads to constant endometrial stimulation with estrogen without progesterone, and thisincreases the risk of endometrial hyperplasia and carcinoma. The Royal College of Obstetricians andGynaecologists (RCOG) recommends induction of withdrawal bleeding with progestogens a minimum of every 3-4months.[4]No known association with breast or ovarian cancer has been found; thus, no additional surveillance is needed.[4]Patient EducationDiscuss with patients the symptoms of polycystic ovarian syndrome (PCOS) as well as their increased risk forcardiovascular and cerebrovascular disease. Educate women with this condition regarding lifestyle modifications
9/7/2017Polycystic Ovarian Syndrome: Practice Essentials, Background, Etiology7/14such as weight reduction, increased exercise, and dietary modifications.[2, 3, 4](See Diet and Activity.)For more information, see Women's Health Center, as well as Ovarian Cysts, Amenorrhea, and Female SexualProblems.Clinical PresentationReferences1. Azziz R, Carmina E, Dewailly D, et al; Task Force on the Phenotype of the Polycystic Ovary Syndrome of TheAndrogen Excess and PCOS Society. The Androgen Excess and PCOS Society criteria for the polycystic ovarysyndrome: the complete task force report.Fertil Steril. 2009 Feb. 91(2):456-88. [Medline].2. Vause TD, Cheung AP, Sierra S, et al. Ovulation induction in polycystic ovary syndrome.J Obstet GynaecolCan. 2010 May. 32(5):495-502. [Medline].3. American College of Obstetricians and Gynecologists. Polycystic ovary syndrome. Washington, DC: AmericanCollege of Obstetricians and Gynecologists; 2009. ACOG practice bulletin; no. 108. [Full Text].4. Royal College of Obstetricians and Gynaecologists. Long-term consequences of polycystic ovary syndrome.London, UK: Royal College of Obstetricians and Gynaecologists; 2007. Green-top guideline; no. 33. [Full Text].5. Consensus on infertility treatment related to polycystic ovary syndrome.Fertil Steril. 2008 Mar. 89(3):505-22.[Medline].6. Barber TM, Franks S. Genetic basis of polycystic ovary syndrome.Expert Review of Endocrinology &Metabolism. 2010. 5(4):549-61.7. Stein I, Leventhal M. Amenorrhea associated with bilateralpolycystic ovaries.Am J Obstet Gynecol. 1935.29:181.8. Stein IF. Duration of infertility following ovarian wedge resection.West J Surg. 1964. 72:237.9. PCOS Consensus Workshop Group. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus WorkshopGroup. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovarysyndrome.Fertil Steril. 2004 Jan. 81(1):19-25. [Medline].

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Endocrinology, Wind, Polycystic ovary syndrome

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