genotypes are 2a 2b Europe Japan 2c Northern Italy 3a 3b India Nepal Pakistan 4

Genotypes are 2a 2b europe japan 2c northern italy 3a

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genotypes are 2a, 2b (Europe, Japan), 2c (Northern Italy), 3a, 3b (India, Nepal, Pakistan), 4 (Africa and Middle East), 5 (South Africa), 6 (Hong Kong and Southeast Asia) (Nouroz, Shaheen, Mujtaba, & Noreen, 2015). Therefore, there are multiple types of treatment based on genotype, therefore the treatment plan for this patient will be for Genotype 1a naïve, non-HIV infected and without cirrhosis. This is due to Genotype 1a being the most prevalent in the United States. The options for treating Genotype 1a are: 1. Epclusa (Sofosbuvir/Velpatasvir), 2. Mavyret (Glecaprevir/Pibrentasvir), Harvoni (Ledipasvir/Sofosbuvir), 4. Zepatier (Elbasvir/Grazoprevir) (Journal of Hepatology, 2018). The patient will need the RNA viral load monitored for 12-16 weeks before starting treatment in the acute phase. So, therefore after that
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time has passed since the scenario said the patient possibly had Hepatitis C. The patient will also have to have a negative drug and alcohol screen before treatment is initiated as treatment is costly and therapy is not initiated until the patient is compliant. The patient will be started on Harvoni treatment which is 90mg Ledipasvir/400mg Sofosbuvir, which is one tablet by mouth daily for eight weeks. This treatment plan does not interfere with any of the current medications the patient is prescribed. References American Association for the Study of Liver Diseases. (2018). HCV Guidelines . Retrieved from Arcangelo, V. P., Peterson, A. M., Wilbur, V., & Reinhold, J. A. (2017). Pharmacokinetics for advanced practice: A practical approach (4th ed.). Ambler, PA: Lippincott Williams & Wilkins.
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