Pharmacology for Dementia The primary goal of drug therapy for patients with

Pharmacology for dementia the primary goal of drug

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Pharmacology for DementiaThe primary goal of drug therapy for patients with dementia is to lessen or stabilize the cognitive changes and increase the patient’s quality of life. Arcangelo and Peterson (2017) recommend the use of cholinesterase inhibitors and memantine to help improve cognitive changes. Cholinesterase inhibitors prevent the breakdown of acetylcholine which is important for learning and memory (Alzheimer’s Association, 2019). Cholinesterase inhibitors include Aricept, Exelon and Razadyne. In cases of moderate to severe disease the addition of memantine has been proven to be effective. It is effective for improvement of memory, attention, reasoning, communication and the ability to perform tasks (Alzheimer’s Association, 2019).Dementia and Age
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Older adults suffering from dementia usually have other comorbidities. Polypharmacy should be considered when prescribing medications for dementia. Elderly may be more susceptible to the adverse effects of cholinesterase inhibitors. Side effects include nausea, vomiting and bradycardia (Arcangelo, Peterson, Wilbur, & Reinhold, 2017). Practitioners should take particular caution when prescribing to the elderly due to other physiological changes associated with aging. ReferencesAlzheimer’s Association. (2019). What is dementia. Retrieved from Arcangelo, V. P., Peterson, A. M., Wilbur, V., & Reinhold, J. A. (2017). Pharmacotherapeutics for advanced practice: A practical approach(4th ed.). Ambler, PA: Lippincott Williams & Wilkins.Habtemariam, S. (2018). Molecular Pharmacology of Rosmarinic and Salvianolic Acids: Potential Seeds for Alzheimer’s and Vascular Dementia Drugs. International Journal Of Molecular Sciences, 19(2). Marcum, Z. A., Hohl, S. D., Gray, S. L., Barthold, D., Crane, P. K., & Larson, E. B. (2019). Brain Health and Dementia Prevention: A Mixed-method Analysis. American Journal of Health Behavior, 43(2), 300–310.
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