{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

05 06 07 Electrophysiology of Neurons and Excitable Cells

Ionic basis of action potential voltage dependencies

Info iconThis preview shows pages 17–28. Sign up to view the full content.

View Full Document Right Arrow Icon
Ionic Basis of Action Potential
Background image of page 17

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Voltage-Dependencies of Na+ and K+ Channels Na+ channels undergo activation (opening), followed by inactivation (closing), during depolarization K+ Channels remain open during depolarization
Background image of page 18
Voltage-Dependencies of Na+ and K+ Channels as Examples of Positive and Negative Feedback Positive Feedback Depolarization  Opening of Na+ Channels  Greater Depolarization Negative Feedback Depolarization  Opening of K+ Channels  Lesser Depolarization
Background image of page 19

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Voltage-Dependencies of Na+ and K+ Channels is the Basic Mechanism of Action Potential
Background image of page 20
Absolute and Relative Refractory Periods
Background image of page 21

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Absolute and Relative Refractory Periods Result in One-Way Propagation of Action Potentials Absolute Refractory Period (Na+ Channel Inactivation) Relative Refractory Period (K+ Channel Activation)
Background image of page 22
Structure of a Neuron
Background image of page 23

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Myelination as Electrical Insulation
Background image of page 24
Axon Myelination and Saltatory Conduction of Action Potentials
Background image of page 25

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Mechanism of Spontaneous Generation of Action Potentials by Sinoatrial Node Pacemaker Potential : Spontaneous depolarization caused by Na+ and Ca2+ influx through hyperpolarization-activated funny channel. Action Potential : Inward Ca2+ current causes SA nodal depolarization; outward K+ current causes SA nodal repolarization.
Background image of page 26
Ionic Basis of Cardiac Action Potential Upstroke Phase of Depolarization : Activation of fast Na+ channels
Background image of page 27

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 28
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

Page17 / 41

Ionic Basis of Action Potential Voltage Dependencies of Na...

This preview shows document pages 17 - 28. Sign up to view the full document.

View Full Document Right Arrow Icon bookmark
Ask a homework question - tutors are online