beta carotene Free Radicals very reactive species electrons like to be in pairs

Beta carotene free radicals very reactive species

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beta-caroteneFree Radicals= very reactive species (electrons like to be in pairs)oA species with a SINGLE electron Formed due to breakage of a chemical bondoFree radicals attack species around it to pick up electrons from healthy cells creating a damaging free radical chain reaction Anti-oxidants convert reactive free radicals into more stable species which are less likely to cause damage oMechanism = antioxidants donate e- to stabilize free radical single e- by pairing it Antioxidants can donate electrons without creating dangerous free radicals (without initiating a chain reaction)Antioxidants = present in our diet and vitamins oAlways better to get it from diet than supplements) Lesson 2: Vitamins IIVIDEO 1Orthomolecular medicine= vitamins can be used to treat more than just nutritional deficiencies oDo not agree with RDA values (i.e. do not believe in the idea of minimal amounts)oExample – RDA for vitamin C = 90mg (to prevent scurvy) but orthomolecular optimum amount = 10,000mgCANNOT get optimumamount from food so you have to get it from supplements Linus Pauling: Dealing with Vitamin C and the Common Cold (orthomolecular medicine) and prevention of heart attack oIDEA = Vit C in large amounts (optimum amounts) can cure the common coldVitamin C and heart disease oDecrease in heart disease and increase of vitamin C Claimed a causative relationship when in fact associativeoHDL cholesterol (GOOD) and LDL cholesterol (BAD) and the oxidized LDL cholesterol (UGLY)
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Plaque formation in the arteries caused by oxidized LDL Antioxidants (like vitamin C) will prevent formation of plaque THUS – diet rich in Vitamin C will prevent risk of heart disease because it will prevent plaque from building up NOT supplementsAlso thought Vit C in diet could prevent cancer in high amounts oBody converts nitrites into cancer-causing chemicals called nitrosamines oVit C prevents the conversion of nitrites to nitrosamine(carcinogen)Vitamin C in the diet can be involved in cancer prevention if the nitrosamine is involved in cancer development Common cold= contagious infection of the upper respiratory tract caused by 200different viruses (i.e. Rhinovirus)oFirst symptom = sneezeLining of nasal passage gets irritated World record for sneeze droplet was 4m and 160km/hrThere is NO causative relationship between cold weather and colds Colds are more prevalent in winter because we spend more time indoors, in closercontact with others Cold remedies do NOT cure colds; they make the symptoms more bearable Epidemiological studies in treating the common coldoUseless: 9000 subjects in 6 countries oBenefits: 16 subjects in USDr. Terrence Anderson concluded that Vitamin C does NOT prevent or cure the common cold but reduces the severity of common cold oVitamin C acts in the same way as cold remedies subside symptomsMost species do not produce vitamin C must be acquired from dietHot dogs contain Sodium AscorbateoHot dogs contain nitrites so ascorbate is added to neutralize its conversion to nitrosamine in the body Claims that vitamin C prevents cataracts and aging The only proven use of vitamin C is for the
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  • Spring '11
  • Multiple
  • Vitamin,  Vitamins

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