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Unformatted text preview: a) Resistance to the new drug by HIV will evolve slower when the base analog mimics the guanine DNA nucleotide less well. b) Resistance to the new drug by HIV will evolve faster when the base analog perfectly mimics the guanine DNA nucleotide. c) Resistance to the new drug by HIV will evolve faster when the drug also acts to increase the population size of HIV. d) Resistance to the new drug by HIV will evolve faster when the drug also acts to decreases the population size of HIV. e) Both answers a & d are correct. Use the following information for the next 5 questions (until you see a solid line): Three strains of an asexual pathogenic bacteria were mistakenly introduced to a hospital when a technician overturned a cart containing 5 flasks of penicillin resistant bacteria, 3 flasks of resistant bacteria, and 2 flasks of streptomycin resistant bacteria. Penicillin, and streptomycin are antibiotics. You can assume that all of the flasks had the same number of bacteria in them. A month later patients were screened for infections by the same strains of bacteria with the following results: 20 cases of penicillin-resistant infections, 60 cases of resistant infections, and 20 cases of streptomycin-resistant infections. You can assume that all resistance alleles map to the same gene, that the bacteria only infects humans, that infected humans carry the same number of bacteria, that the bacteria were absent from the hospital prior to the accident, and that one generation transpired before the patients were sampled. 66) The frequency of the allele in the gene pool of bacteria released into the hospital immediately after the accident was: A) 0.1 B) 0.3 C) 0.5 D) 0.6 E) 0.9 67) Assuming that the total number of bacteria is the same at the time of the spill and the sampling of patients, then the Darwinian fitness of the streptomycin-resistant phenotype is: A) 0 B) 1 C) 2 D) 5 E) 10 68) The relative fitness of the penicillin-resistant phenotype is: A) 0.0 B) 0.1 C) 0.2 D) 0.5 E) 1.0 69) The best ‘gene transport machine’ is the: A) -resistance gene B) Streptomycin-resistant phenotype C) Penicillin resistance gene D) Penicillin-resistance phenotype E) None of these answers 70) If you were admitted to the hospital a little more than a month after the accident, which single antibiotic would provide the least protection from this infective agent? A) B) Penicillin C) Streptomycin D) Penicillin & E) Streptomycin & _____________________________________________________________________________ Use the following information for the next 3 questions (until you see a solid line): A new drug is developed to fight HIV/AIDS that binds to the CCR5 protein and thereby prevents other molecules from binding to it. The drug is given to a group of high-risk uninfected individuals. There was also a matched control group (uninfected) that did not receive the drug....
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- Winter '07
- hiv virus, CD4+ Helper