lecture 2 review handout with answers

What does it mean for a cell to be fated fate

Info icon This preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
What does it mean for a cell to be “fated ”? Fate describes how the cell would normally develop, and can be traced by following individual cells during development to see what they become. Fate does NOT dictate the state of commitment in a cell 4. What does it mean for a cell to be “committed ”? Requires an operational test to distinguish between specification and determination. Specification Test: If when isolated from embryo and cultured in a NEUTRAL environement cell develops according to its normal fate. Presumptive eye region of BLASTULA when neutrally cultured does not express gene characteristics of eye differentiation, yet the presumptive eye region of a GASTRULA, when neutrally cultured expresses genes characteristics of eye differentiation.
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Determination: A stable change inn the internal state of a cell, an irreversible commitment to a specific fate, heritable upon division. Test: transplant cells to a challenging environment. Presumptive eye region of GASTRULA adopts regional characteristics (rather than eye characteristics). Presumptive eye region of NEURULA retains eye characteristics upon transplantation to challenging environment.
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern