Brief Mechanism of Action Disrupts DNA and protein synthesis in susceptible

Brief mechanism of action disrupts dna and protein

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Brief Mechanism of Action : Disrupts DNA and protein synthesis in susceptible organisms Onset; Peak; Duration Rapid, end of infusion, 6-8 hours Therapeutic Effectiveness (How will you know the medication is working?): Bactericidal, trichomonacidal, or amoebicidal action Major/Significant Side Effects: SEIZURES, dizziness, headache, aseptic meningitis (IV), encephalopathy (IV), psychosis, abdominal pain, anorexia, nausea, diarrhea, dry mouth, furry tongue, glossitis, unpleasant taste, vomiting, STEVENS-JOHNSON SYNDROME, rash, urticaria topical only: burning, mild dryness, skin irritation, transient redness, leukopenia, phlebitis at IV site, peripheral neuropathy, superinfection Significant Nursing Implications : 1.Assessment: assess for LOC, infection, rash, I&O and daily weight, C&S before start of therapy, giardiasis 2.Dietary: avoid alcohol 3.Labs: May alter results of serum AST, ALT, and LDH tests. 4.Contraindications: Hypersensitivity; Hypersensitivity to parabens (topical only); OB: First trimester of pregnancy 5.Antidotes: n/a 6. Teaching: take as directed, no alcohol, may leave metallic taste in mouth, good oral hygiene, may make urine dark in color, may cause dizziness and drowsiness, notify HCP for signs of super infection and if it doesn’t improve in few days 7. Miscellaneous: Advise patient to inform health care professional if pregnancy is suspected before taking this medication or if breast feeding \
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2.Dietary: 3.Labs: 4.Contraindications: 5.Antidotes: 6. Teaching: 7.. Miscellaneous: \ Medication Medication
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