“Off-label” prescribing should be aimed at benefiting the individual patient, and provider must use their best professional judgement to facilitate the best care for their patients. Strategies Used to Make Off-Label Prescribing Safer for Children To make “off label” prescribing safer in children, clinical trials should be conducted and encouraged to improve drug safety. Prescribers should adhere to the professional code of ethics taking care to report any adverse reactions, medication errors, and “off-label” use. Also,
pediatric investigation plans (PIPs) should be implemented to achieve appropriate drug licenses for use in children. Off-Label Drugs Requiring Extra Attention and Care for Pediatrics Drugs commonly requiring extra care and attention when administering them to pediatric patients include: oxycodone, dexmedetomidine, hydromorphone, lorazepam, ketamine, methadone, milrinone, and dopamine. References American Academy of Pediatrics. (2014, March). Off-label use of drugs in children. Pediatrics, 133(3) , 563-567. doi:10.1542/peds.2013-4060. Retrieved from Arcangelo, V. P., Peterson, A. M., Wilbur, V., & Reinhold, J. A. (Eds.). (2017).
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