Treating BPH Rauwolfia vomitoria – African snakeroot Strophanthus kombe - Kombe 2
Aloe vera – the burn plant / medicine plant North Africa. Alexander the great first used aloe vera and conquered the areas that had aloe vera Succulent (fleshy) leaves are used. Aloe latex contains a glycoside, aloin . Used as a laxative Aloe gel contains saponins, sterols, and salicylic acid. For treating burns & skin disorders. o Saponin acts as a soap o Sterol to prevent infections o Salicylic acid for anti-inflammatory The aloe extract contains both the latex and gel Catha edulis – Khat tree S and E Africa to Afghanistan Fresh leaves are chewed. Used as a stimulant Accepted in Afro-Arabian cultures. Calcium hydroxide added to the leaves help to extract the chemical compounds Chemical compounds: cathine, cathinone Cathine: an alkaloid Cathinone: CNS stimulant, banned in many places, UK and US Long term uses result in constipation, decreased appetite, irritability & low sexual drive. Strophanthus kombe – Kombe S., E. and W. Africa Apocynaceae “milk weeds”, same family Mano tribe in Liberia “cure all plant” Natives used them in trials by ordeal o Used on the criminal as a punishment in order to determine in the person is guilty or not based on the person’s reaction to the seeds Seeds contain cardiac glycosides. S. gratus - Strophantus o Plants are toxic, used in arrow poisons in Africa o “poison arrow plant” o Chemical compound: ouabain from S. gratus is also used commercially as a cardiotonic agent In both, seeds contain cardiac glycosides Both species contain straphanthin discovered in 1885 And sarmentogenin, a precursor for cortisone for treating arthritis o Traditionally in the US Ox bile was used as cortisone precursor 3
o Straphanthus seeds are 17 chemical steps closer to cortisone than Ox bile o William Laurence – a science writer won a Pulitzer Prize The Middle East The Middle East is known as the cradle of civilization Many modern crops were first domesticated in this region. Assyrians, Babylonians, and Sumerians recorded herbal remedies in clay tablets (dated 2000-4000 BCE) Sumerian clay tablets are thought to be the oldest known prescription pads Wall paintings of tombs in Egypt (2700-2200 BCE) include that of poium poppy capsules The Code of Hammurabi (ca. 1700 BCE) lists several hundred medicinal herbs in a series of several hundred clay tablets carved under the direction of king of Babylon These tablets mention henbane, licorice, and mint that are still used in medicine today. Bible records several medicinal plants dating back to 1500 BCE Ebers Papyrus- a 20m papyrus scroll (1500 BCE) lists >700 medicinal recipes based on plants.
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