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Capsid removed – virus exists as nucleic

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Unformatted text preview: Capsid removed – Virus exists as nucleic acid (genetic material) Image: Viral life cycle , National Academy of Sciences; Bacteriophage injecting DNA into bacterial cell , Graham Colm. Remember, a virus can exist outside of its host or inside its host. So we need some more terms: 2. How does a virus infect its host? From the Virtual Microbiology Classroom on ScienceProfOnline.com Image: Bacteriophage injecting DNA into bacterial cell , Graham Colm 2a. How does a bacteriophage infect its host? From the Virtual Microbiology Classroom on ScienceProfOnline.com Entry of Viruses into Animal Cells – 3 Methods : 1. Direct penetration of naked virus- Viral genome enters cell, while capsid remains on cell’s surface. Like how phages enter bacteria. Remember the endomembrane system of eukaryotes? 2. Endocytosis 3. Membrane fusion- With membrane fusion and endocytosis, the capsid is removed once inside the host cell. Images: Virus Entry into Cell ; Endocytosis & Exocytosis , NIGMS; Endocytosis & exocytosis, Nicolle Rager Fuller, NSF 2b. How does an animal virus infect its host? Let’s review that animation on endocytosis & exocytosis From the Virtual Microbiology Classroom on ScienceProfOnline.com Image: Mechanisms of Viral entry into host cells , NCBI, US Gov. 2b. How does an animal virus infect its host? Examples of Animal Virus Entry From the Virtual Microbiology Classroom on ScienceProfOnline.com Four basic steps: 1. Recognize & attach to host cell. 2. Infect (get inside) host cell. 3. Force cell to manufacture viruses. 4. New viruses exit the host cell. Image: Source unknown . How Do Viruses Reproduce? From the Virtual Microbiology Classroom on ScienceProfOnline.com 3. How does the infecting virus trick the host into manufacturing more viruses? • Host cell reads viral genetic instructions and manufactures raw materials needed to build copies of new viruses....
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Capsid removed – Virus exists as nucleic acid(genetic...

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