communication needs if
applicable
splinting incision
ICU
Post-op
promote ventilation
chest tubes
promote comfort
I&O
pneumonectomy
no chest tubes
position on back,
operative side
check for mediastinal
shift
Discharge
arm exercises
wound care, s/s infection
follow-up
radiation/chemotherapy
Radiation and chemotherapy
palliation for pain control

Leukemia
Leukemia
Types of Leukemia
Treatments
Nursing process
Leukemia “White blood”
Group of chronic malignant
disorders of WBCs/ precursors
replacement of bone marrow by
malignant, immature, circulating
WBCs
infiltration of cells into liver,
spleen, lymph nodes
Incidence and Risk factors
Adult:
10 times more frequent
than children
Genetic:
Down syndrome
Environmental:
exposure to
cigarette smoking, benzene
chemicals in gasoline, ionizing
radiation
Pathophysiology
Stem cell malignancy: accumulate
in bone marrow
Immature cells replace normal
hematopoietic elements
Results in severe anemia,
splenomegaly, and bleeding
difficulties
infiltrate to CNS, testes, GI tract,
lymph nodes, liver, spleen
Classifications
Acute:
acute onset, rapid disease
progression, immature blast cells
Chronic:
gradual onset, prolonged
course, abnormal mature cells
Lymphocytic:
immature
lymphocytes/ precursor bone
marrow cells
Myeloid:
myeloid stem cells,
decreased maturation of
granulocytes RBCs and
thrombocytes
Type of Leukemia
Acute lymphocytic (ALL)
Chronic lymphocytic (CLL)
Acute myeloid (AML)
Chronic myeloid (CML)
Acute lymphocytic (ALL)
Myeloblast (precursors of
granulocytes) proliferation and bone
marrow/spleen hyperplasia
Common in older adults
Neutropenia (severe infection) and
thrombocytopenia (bruising,
hematuria, GI bleeding)
Chemotherapy, SCT
Chronic Myeloid Leukemia
Abnormal proliferation of all bone
marrow elements
Onset 30, 40, or 50 years
Chromosome abnormality
(Philadelphia chromosome),
translocation of chromosome 22 to 9
Terminal blast crisis-later
progression to acute leukemia with
blast cell proliferation and skin, lymph
node, bone, CNS infiltration
Interferon alpha: chemotherapy,
SCT
Acute Lymphocytic Leukemia
Malignant immature B cells
(lymphoblasts) proliferate in bone
marrow
Thromobocytopenia, leukopenia
and anemia
Chemotherapy: complete remission
in 80% of adults
Chemotherapy; BMT, or SCT
Chronic Lymphocytic Leukemia
Abnormal, mature, B lymphocyte
proliferation in bone marrow,
peripheral blood, body tissues
Older adults (65 and older)
Often requires no treatment;
chemotherapy, BMT
Diagnosis
CBCD
: evaluates cell counts, H&H
number, distribution, size and shape of
WBCs
Plt:
identify thrombocytopenia and
bleeding risk
Bone marrow examination:
identify
cell marrow information, type of
erythropoiesis, maturity of
erythropoietin and leukopoietic cells
Chemotherapy
Single agent or combination
Induction phase
: high doses to
eradicate leukemic, cells
Colony stimulating factors:


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- Fall '16
- Karen Price
- Nursing