PHRM 514 STD's Fall 2012 (1)

Sexually transmitted diseases in dipiro jt talbert rl

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Unformatted text preview: Sexually transmitted diseases. In: DiPiro JT, Talbert RL, Yee GC, et al., editors. Pharmacotherapy a pathophysiologic approach. 8th ed. New York: McGraw Hill Medical; 2011:2011-2028. Genital Herpes: Complications n Lesions at extragenital sites § Eye § Rectum § Pharynx § Fingers n CNS involvement Knodel, LC. Sexually transmitted diseases. In: DiPiro JT, Talbert RL, Yee GC, et al., editors. Pharmacotherapy a pathophysiologic approach. 8th ed. New York: McGraw Hill Medical; 2011:2011-2028. Neonatal Herpes n High morbidity and mortality § Fatality rate of 50% n Transmitted via exposure to HSV in the birth canal § Rarely transplacentally n Risk greater for 1st episode primary infections n May lead to permanent neurologic damage Knodel, LC. Sexually transmitted diseases. In: DiPiro JT, Talbert RL, Yee GC, et al., editors. Pharmacotherapy a pathophysiologic approach. 8th ed. New York: McGraw Hill Medical; 2011:2011-2028. Genital Herpes: Diagnosis n Genital ulcers or mucocutaneous lesions § Culture or PCR n Type specific antibody tests available to distinguish HSV1 and HSV2 Knodel, LC. Sexually transmitted diseases. In: DiPiro JT, Talbert RL, Yee GC, et al., editors. Pharmacotherapy a pathophysiologic approach. 8th ed. New York: McGraw Hill Medical; 2011:2011-2028. Centers for Disease Control and Prevention. Sexually Transmitted Diseases Treatment Guidelines. MMWR 2010;59(RR-12):1-116. Trichomoniasis Trichomoniasis Statistics n Estimated overall prevalence 2001-2004 = 3.1% Centers for Disease Control and Prevention. Sexually Transmitted Disease Surveillance 2010. Atlanta: U.S. Department of Health and Human Services; 2011. Trichomoniasis n Trichomonas vaginalis n Flagellated, motile protozoan n Most commonly spread through sexual contact n May survive on moist surfaces up to 45 minutes § Communal bathing § Infected bath or toilet articles n More common in females than males Knodel, LC. Sexually transmitted diseases. In: DiPiro JT, Talbert RL, Yee GC, et al., editors. Pharmacotherapy a pathophysiologic approach. 8th ed. New York: McGraw Hill Medical; 2011:2011-2028. Trichomoniasis: Pathophysiology 1. Trichomonads attach to vaginal or urethral mucosa 2. Elicit an inflammatory response 3. Manifests as discharge containing large numbers of PMN leukocytes Knodel, LC. Sexually transmitted diseases. In: DiPiro JT, Talbert RL, Yee GC, et al., editors. Pharmacotherapy a pathophysiologic approach. 8th ed. New York: McGraw Hill Medical; 2011:2011-2028. Trichomoniasis: Clinical Presentation Males Females Incubation Period 3-28 days 3-28 days Most Common Site of Infection Urethra Endocervical canal Other Sites of Infection Rectum, eye, oropharynx Urethra, eye, rectum, oropharynx Knodel, LC. Sexually transmitted diseases. In: DiPiro JT, Talbert RL, Yee GC, et al., editors. Pharmacotherapy a Knodel, LC....
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Sexually transmitted diseases In DiPiro JT Talbert RL Yee...

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