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Lecture_16_-Gases

This is converted to nitric acid and leads to acid

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(NO2). This is converted to nitric acid and leads to “acid rain.” Biological NO: - extremely reactive and potentially dangerous free radical produced by the body History of Clinical Application of “NO” -nitroglycerin is a component of dynamite-that was created by Alfred Nobel -use of dynamite during war caused Alfred Nobel to create the Nobel Peace Prize -in late 1800’s nitroglycerin was administered in a diluted form to help people with cardiovascular problems; for the last 2 months of his life Alfred Nobel was treated for angina with dilute nitroglycerin (Trinitrin) -in 1970’s the secret of nitroglycerin’s relationship with NO emerged and NO identified as a signaling molecule released by endothelia cells that relaxed blood vessles and . -The 1998 Nobel Prize in Medicine was awarded to Robert Furchgott, Ferid Murad and Louis Ignarro for their discoveries in how NO regulated the muscle tone of blood vessels in the cardiovascular system. -Endothelium-Derived Relaxing Factor (EDRF)
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• NO regulates the muscle tone of blood vessels to have a major impact on controlling blood pressure. • NO causes penile erections and increases genital sensitivity in both men and women by dilating blood vessels (Viagra). • NO stops blood platelet cells from grouping together in a clot to help prevent blockages in the blood vessels (. • NO controls the action of almost every orifice from swallowing to defecation. • NO helps the immune system fight viral, bacterial and parasitic infections as well as tumors. • NO transmits messages
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This is converted to nitric acid and leads to acid rain...

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