Antagonism of BMP4 signaling disrupts smooth muscle investment of the ureter

Antagonism of bmp4 signaling disrupts smooth muscle

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Antagonism of BMP4 signaling disrupts smooth muscle investment of the ureter and ureteropelvic junction. J Urol 181: 401–407. 24. Grigoryan T, Wend P, Klaus A, Birchmeier W (2008) Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain- of-function mutations of beta-catenin in mice. Genes Dev 22: 2308–2341. 25. Pietila I, Ellwanger K, Railo A, Jokela T, Barrantes Idel B, et al. Secreted Wnt antagonist Dickkopf-1 controls kidney papilla development coordinated by Wnt- 7b signalling. Dev Biol 353: 50–60. 26. Tasouri E, Tucker KL (2011) Primary cilia and organogenesis: is Hedgehog the only sculptor? Cell Tissue Res 345: 21–40. 27. Hahn H, Wicking C, Zaphiropoulous PG, Gailani MR, Shanley S, et al. (1996) Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 85: 841–851. 28. Johnson RL, Rothman AL, Xie J, Goodrich LV, Bare JW, et al. (1996) Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 272: 1668–1671. 29. Taylor MD, Liu L, Raffel C, Hui CC, Mainprize TG, et al. (2002) Mutations in SUFU predispose to medulloblastoma. Nat Genet 31: 306–310. 30. Hu MC, Mo R, Bhella S, Wilson CW, Chuang PT, et al. (2006) GLI3- dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis. Development 133: 569–578. 31. Cain JE, Islam E, Haxho F, Chen L, Bridgewater D, et al. (2009) GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cells. PLoS One 4: e7313. 32. Yu J, Carroll TJ, McMahon AP (2002) Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney. Development 129: 5301–5312. 33. Lu J, Richardson JA, Olson EN (1998) Capsulin: a novel bHLH transcription factor expressed in epicardial progenitors and mesenchyme of visceral organs. Mech Dev 73: 23–32. 34. Robb L, Mifsud L, Hartley L, Biben C, Copeland NG, et al. (1998) epicardin: A novel basic helix-loop-helix transcription factor gene expressed in epicardium, branchial arch myoblasts, and mesenchyme of developing lung, gut, kidney, and gonads. Dev Dyn 213: 105–113. 35. Robyn J. Quinlan JLT, and Philip L Beales (2008) Modeling Ciliopathies: Primary Cilia in Development and Disease. Current Topics in Developmental Biology, Volume 84: 250–310. 36. Attanasio M, Uhlenhaut NH, Sousa VH, O’Toole JF, Otto E, et al. (2007) Loss of GLIS2 causes nephronophthisis in humans and mice by increased apoptosis and fibrosis. Nat Genet 39: 1018–1024. Generation of Tcf21/Pod1-Cre Mouse PLoS ONE | 8 July 2012 | Volume 7 | Issue 7 | e40547
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  • Fall '20
  • john
  • The Land, Nephron, PLOS One, mesenchyme, hydroureter

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