What is an indication for the use of estrogen receptor modulators A

What is an indication for the use of estrogen

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QuestionQuestionWhat is an indication for the use of estrogen receptor modulators? A. Postmenopausal osteoporosisB. Hereditary angioedemaC. Osteogenesis imperfectaD. Breast cancer
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Copyright © 2017 Wolters Kluwer • All Rights Reserved AnswerAnswerA. Postmenopausal osteoporosisRationale: The indication for estrogen receptor modulators is postmenopausal osteoporosis.
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Fertility Drugs Fertility Drugs Stimulate the female reproductive system Cetrorelix ( Cetrotide ), Chorionic gonadotropin ( Pregnyl ) Chorionic gonadotropin alpha ( Ovidrel ), Clomiphene ( Clomid , and others) Follitropin alfa ( Gonal-F ) Follitropin beta ( Follistim AQ ), ganirelix (generic), menotropins ( Pergonal ) Urofollitropin( Bravelle )
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Fertility Drugs Fertility Drugs Actions Directly or by stimulating the hypothalamus to increase FSH and LH levels, leading to ovarian follicular development and maturation of ova Indications Infertility in men and women Pharmacokinetics Well absorbed, undergo hepatic metabolism and renal excretion
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Fertility Drugs (cont.) Fertility Drugs (cont.) Contraindications Primary ovarian failure Thyroid or adrenal dysfunction Ovarian cysts Pregnancy, idiopathic uterine bleeding, and known allergy Caution Breast feeding, thromboembolic disease, or respiratory disease
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Fertility Drugs (cont.) Fertility Drugs (cont.) Adverse Effects Increase risk of multiple births and birth defects Ovarian overstimulation Headache, fluid retention, nausea, bloating Uterine bleeding, ovarian enlargement Gynecomastia
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Nursing Considerations for Patients Receiving Fertility Drugs Nursing Considerations for Patients Receiving Fertility Drugs Assess- History and physical Known allergy Primary ovarian failure or thyroid or adrenal dysfunction Uterine bleeding, pelvic and breast examinations and appropriate lab values
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Prototype Fertility Drugs
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Prototype Fertility Drugs (Continued) Prototype Fertility Drugs (Continued)
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Oxytocics Oxytocics Stimulate uterine contractions to assist labor (oxytocics) or induce abortion (ab Methylergonovine ( Methergine ), and oxytocin ( Pitocin)
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Oxytocics Oxytocics Actions Affect neuroreceptors sites to stimulate contractions of the uterus Indications Prevention and treatment of uterine atony after delivery Pharmacokinetics Rapidly absorbed, metabolized in the liver, and excreted in urine and feces
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Oxytocics (cont.) Oxytocics (cont.) Contraindications Allergy and early pregnancy Cephalopelvic disproportion Caution Coronary artery disease, hypertension, lactation, and previous Cesarean section
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