Proteins we often consider the number of polar groups

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proteins, we often consider the number of polar groups within the molecule to determine the extent to which the overall molecule is polar. Example 1) from page 1 of Lecture 13 notes: The significance of polarity in vitamins For example, let’s compare vitamin A to vitamin B9 Which vitamin contains a higher number of polar bonds? vitamin ________ Vitamin A Vitamin B9 (folic acid) ________________ soluble ________________ soluble H 2 C H 2 C C H 2 C C H C C H C H H C C H C C H H 2 C O H 3 C CH 3 CH 3 CH 3 CH 3 H C HC C H C CH H C N H C N H O HC H 2 C CH 2 C OH C O HO O H 2 C C HC N C C N N C N C O NH 2 H
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Vitamin B9 ( folic acid ) has many more polar bonds than vitamin A. Since fat is non- polar and water is polar, vitamin A is water soluble and vitamin B9 is fat soluble (like dissolves like). Polar bonds in vitamin A: H 2 C H 2 C C H 2 C C H C C H C H H C C H C C H H 2 C O H 3 C CH 3 CH 3 CH 3 CH 3 H Polar bonds in folic acid (vitamin B9): C HC C H C CH H C N H C N H O HC H 2 C CH 2 C OH C O HO O H 2 C C HC N C C N N C N C O NH 2 H Let’s think about what this means in terms of our daily multivitamins. Folic acid (vitamin B9) is water soluble, which means it is excreted in our urine comparatively quickly from our bodies.
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