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Pancreas and gastrointestinal function objectives

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PANCREAS AND GASTROINTESTINAL FUNCTION –OBJECTIVES sensitive indicator to acute pancreatitis; the magnitude of the enzyme elevated cannot be correlated w/ the severity of the disease Lipase Testing Increases in serum about as soon as AMY does in acute pancreatitis and that increased level persists somewhat longer than those of AMY; more specific for acute pancreatitis Sweat Chloride Testing Normally done on babies; small level of electrical current stimulates sweat; look for abnormal secretions; like a screening test; of high amounts send off for genetic testing; Iontophoresis -pilocarpine administered –electrical current causes penetration into the skin-sweat production- analyzed for chloride; inc. x 5 in children >60 mmol/L; confirm w/ CF mutation test Lactose Tolerance Test Test of intestinal function; ingest lactose and measure blood glucose to assess absorption and conversion to glucose; the disaccharide lactase cleaves lactose into glucose and galactose and is produced by the mucosal cells of the small intestine; congenital deficiencies of this enzyme are rare but acquired deficiencies of lactase in commonly found in adults; symptoms= abdominal discomfort, cramps, and diarrhea after ingesting milk or milk products; 75% of A.A. are affected Describe Physiological Causes of Gastric Secretion Neurological impulses from the brain transmitted by means of vagal nerves (i.e. response to sight, smell, or anticipation of food); distention of stomach with food or fluid; contact of protein
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