PHRM 514 STD's Fall 2012 (1)

Sexually transmitted diseases in dipiro jt talbert rl

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Unformatted text preview: Sexually transmitted diseases. In: DiPiro JT, Talbert RL, Yee GC, et al., editors. Pharmacotherapy a pathophysiologic approach. 8th ed. New York: McGraw Hill Medical; 2011:2011-2028. Trichomoniasis: Clinical Presentation Males Females Symptoms Asymptomatic or minimally symptomatic Clear to purulent urethral discharge, dysuria, pruritus Asymptomatic or minimally symptomatic Scant to copious, malodorous, vaginal discharge, pruritus, dysuria, dysparenunia Signs Urethral discharge Vaginal discharge, vaginal pH 4.5-6, inflammatory/erythema of vulva, vagina, and/or cervix, urethritis Knodel, LC. Sexually transmitted diseases. In: DiPiro JT, Talbert RL, Yee GC, et al., editors. Pharmacotherapy a pathophysiologic approach. 8th ed. New York: McGraw Hill Medical; 2011:2011-2028. Trichomoniasis: Complications Males Females Complications n Epididymitis and chronic prostatitis n Infertility n Pelvic inflammatory disease • May lead to ectopic pregnancy, infertility n Premature labor, premature rupture of membranes, low birth weight infants n Cervical neoplasia Knodel, LC. Sexually transmitted diseases. In: DiPiro JT, Talbert RL, Yee GC, et al., editors. Pharmacotherapy a pathophysiologic approach. 8th ed. New York: McGraw Hill Medical; 2011:2011-2028. Trichomoniasis: Diagnosis n Vaginal discharge pH § T. vaginalis requires pH range of 4.9 to 7.5 for survival § Vaginal discharge pH of >5 usually indicates presence of T. vaginalis or Gardnerella vaginalis n Wet-mount microscopic examination of vaginal discharge § Confirmed if presence of pear-shaped, flagellating organisms n Cultures § Highly specific and sensitive § May use for confirming diagnosis n Monoclonal antibody, DNA probe techniques or PCR tests § Detect small amounts of trichomonal DNA § Highly sensitive and specific § Can use vaginal and urine samples Knodel, LC. Sexually transmitted diseases. In: DiPiro JT, Talbert RL, Yee GC, et al., editors. Pharmacotherapy a pathophysiologic approach. 8th ed. New York: McGraw Hill Medical; 2011:2011-2028. Trichomonas Vagin alis Under a Microscope Trichomoniasis - CDC Fact Sheet . Centers for Disease Control and Prevention. http://www.cdc.gov/std/trichomonas/STDFact-Trichomoniasis.htm. Updated August 3, 2012. Accessed October 17, 2012. Questions? n Email: [email protected] n Office Hours: by appointment...
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Sexually transmitted diseases In DiPiro JT Talbert RL Yee...

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